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Naprosyn Drug Center

Medical Editor: Charles Patrick Davis, MD, PhD

Naprosyn (also termed naproxen, EC-Naprosyn and Anaprox/Anaprox DS), is a proprionic acid derivative and is considered as a member of the nonsteroidal anti-inflammatory drug (NSAIDs) group. Naprosyn is available as a generic drug termed naproxen. All the Naprosyn drugs are used for pain management for many diseases, arthritic diseases, and inflammatory diseases such as tendonitis, bursitis, and gout. The most common side effects of Naprosyn are gastrointestinal; heartburn, abdominal pain, nausea, diarrhea, or constipation. Other side effects may include headache, visual and hearing changes, and itching.

Naprosyn is available in several doses and drug configurations; Naprosyn tablets with strengths of 250, 375 and 500 mg and as an oral suspension containing 125 mg Naprosyn per 5 ml of liquid, EC-Naprosyn (delayed release to reduce gastric irritation) with strengths of 375 and 500 mg, Anaprox in 275 mg tablets, Anaprox DS in 550 mg tablets. Almost all Naprosyn drugs are recommended to be dosed twice per day (every 12 hours) with children's doses (strength in mg per Kg) based on the child's weight, also twice a day with a maximum dose of 15 mg per Kg per day. Individuals with renal problems should avoid taking Naprosyn. Possible (usually less than 1% of patients) severe side effects are gastric ulcers and GI bleeding, anemia, renal function impairment, liver impairment, pancreatitis, colitis, convulsions, cardiac problems, severe skin changes, and mental status changes. Naprosyn can increase the effects of Eskalith, Lithobid (lithium) and Coumadin (warfarin) and decrease the effects of Rheumatrex, Trexall (methotrexate), diuretics, ACE inhibitors, and thiazides. Naprosyn may cause premature closing of the ductus arteriosus in the fetus and does enter breast milk; avoidance of the drug in pregnant and breastfeeding women is suggested.

Our Naprosyn Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases, and conditions.