Nascobal (Cyanocobalamin) Patient Information: How Should I Take the Drug at RxList

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May 27, 2012

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Crohn's Disease »

What is Crohn's disease?

Crohn's disease (also spelled Crohn disease) is a chronic inflammatory disease of the intestines. It primarily causes ulcerations (breaks in the lining) of the small and large intestines, but can affect the digestive system anywhere from the mouth to the anus. It is named after the physician who described the disease in 1932. It also is called granulomatous enteritis or colitis, regional enteritis, ileitis, or terminal ileitis.

Crohn's disease is related closely to another chronic inflammatory condition that involves only the colon called ulcerative colitis. Together, Crohn's disease and ulcerative colitis are frequently referred to as inflammatory bowel disease (IBD). Ulcerative colitis and Crohn's disease have no medical cure. Once the diseases begin, they tend to fluctuate between periods of inactivity (remission) and activity (relapse).

Inflammatory bowel disease affects approximately 500,000 to two million peop...

Read the Crohn's Disease article »

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Nascobal Patient Information including How Should I Take

Who should not use cyanocobalamin nasal (Nascobal)?

Before using this medication, tell your doctor if you have Leber's disease. Cyanocobalamin nasal may lead to optic nerve damage and possibly blindness when used by people with this condition.

When using the nasal spray, tell your doctor if you develop nasal congestion, a cold, or allergies. The nasal spray may not work as well if you are congested.

Cyanocobalamin nasal is in the FDA pregnancy category C. This means that it is not known whether cyanocobalamin nasal will harm an unborn baby. Vitamin B12 is important to the proper development of a baby. Talk to your doctor about using this medication if you are pregnant.

Cyanocobalamin nasal passes into breast milk. Vitamin B12 is necessary for both mother and child during breast-feeding. Talk to your doctor about using this medication during breast-feeding.

How should I use cyanocobalamin nasal (Nascobal)?

Use cyanocobalamin nasal exactly as directed by your doctor. If you do not understand these directions, ask your doctor, nurse, or pharmacist to explain them to you.

To use the nasal gel:

Gently blow your nose to clear any mucous.
Uncap the pump. Prime the unit (on first use and after 48 hours without use) by pumping it seven to eight times until a gel droplet appears at the tip. Then prime the unit with an additional two sprays.
Insert the tip about 1 centimeter (one-third inch) into your nostril, pointing it towards the back of the nose.
Block your other nostril and tilt your head forward.
Pump and sniff gently at the same time.
Remove the pump from your nose. Rub your nostril gently for a few seconds.
Clean the pump nozzle with a tissue and recap.

Use only one dose in one nostril unless otherwise directed. The nasal gel is usually used once a week to treat pernicious anemia.

Use the nasal spray 1 hour before or after eating or drinking hot foods or liquids.

To treat pernicious anemia, you will have to use this medication on a regular basis for the rest of your life. Failure to do so will result in irreversible damage to the nerves of your spinal cord. Also, treatment with cyanocobalamin nasal cannot be replaced with folic acid therapy. Folic acid may prevent anemia, but it will allow progressive damage to the spinal cord.

Store this medication at room temperature away from moisture, heat, and light. Keep the nasal gel in the prescription vial when it is not in use.

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