Nasonex (Mometasone Furoate (nasal spray)) Drug Information: Overdosage and Contraindications

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May 27, 2012

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Allergy »

Allergy facts

Allergy involves an exaggerated response of the immune system.
The immune system is the body's organized defense mechanism against foreign invaders, particularly infections.
Allergens are substances that are foreign to the body and can cause an allergic reaction.
IgE is the allergy antibody.
Allergies can develop at any age.
Your risk of developing allergies is related to your parents' allergy history.

Introduction

In this review you will learn how allergy relates to the immune system. You will begin understanding how and why certain people become allergic. The most common allergic diseases are discussed briefly in this article.

What does an allergy mean?

An allergy refers to an exaggerated reaction by our immune system in response to bodily contact with certain foreign substances. It is exaggerated because these f...

Read the Allergy article »

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OVERDOSE

There are no data available on the effects of acute or chronic overdosage with NASONEX (mometasone furoate (nasal spray)) Nasal Spray 50 mcg. Because of low systemic bioavailability, and an absence of acute drug-related systemic findings in clinical studies, overdose is unlikely to require any therapy other than observation. Intranasal administration of 1600 mcg (4 times the recommended dose of NASONEX (mometasone furoate (nasal spray)) Nasal Spray 50 mcg for the treatment of nasal polyps in patients 18 years of age and older) daily for 29 days, to healthy human volunteers, showed no increased incidence of adverse events. Single intranasal doses up to 4000 mcg and oral inhalation doses up to 8000 mcg have been studied in human volunteers with no adverse effects reported. Chronic over dosage with any corticosteroid may result in signs or symptoms of hypercorticism [see WARNINGS AND PRECAUTIONS]. Acute overdosage with this dosage form is unlikely since one bottle of NASONEX (mometasone furoate (nasal spray)) Nasal Spray 50 mcg contains approximately 8500 mcg of mometasone furoate.

CONTRAINDICATIONS

NASONEX (mometasone furoate (nasal spray)) Nasal Spray is contraindieated in patients with known hypersensitivity to mometasone furoate or any of its ingredients.

Last reviewed on RxList: 3/7/2011
This monograph has been modified to include the generic and brand name in many instances.