"The U.S. Food and Drug Administration today approved Dotarem (gadoterate meglumine) for use in magnetic resonance imaging (MRI) of the brain, spine and associated tissues of patients ages 2 years and older.
Dotarem is a gadolinium-based"...
Overdosage has not been reported with NebuPent (pentamidine isethionate) . The symptoms and signs of overdosage are not known.
A serious overdosage, to the point of producing systemic drug levels similar to those following parenteral administration, would have the potential of producing similar types of serious systemic toxicity. (See PRECAUTIONS).
Available clinical pharmacology data (see CLINICAL PHARMACOLOGY) suggest that a dose up to 40 times the recommended NebuPent (pentamidine isethionate) dosage would be required to produce systemic levels similar to a single 4 mg/kg intravenous dose.
NebuPent (pentamidine isethionate) is contraindicated in patients with a history of an anaphylactic reaction to inhaled or parenteral pentamidine isethionate.
Last reviewed on RxList: 4/4/2011
This monograph has been modified to include the generic and brand name in many instances.
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