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Neggram Caplets
E. coli 0157:H7 Facts
- E. coli 0157:H7 is a gram-negative bacterium that can produce a bloody diarrhea due to toxins it secretes when it infects human intestinal tracts.
- The symptoms of E. coli 0157:H7 infection may include a low fever, nausea, vomiting, stomach cramps, and bloody diarrhea.
- E. coli 0157:H7 is notorious because it can cause additional complications in children and the elderly; renal failure, anemia, and dehydration especially for children (termed HUS or Hemolytic-uremic syndrome) and spontaneous bleeding, organ failures, and mental changes in the elderly (termed TTP or thrombotic thrombocytopenic purpura). Some of these patients develop disabilities or die.
- Diagnosis is definitively made when E. coli 0157:H7 is isolated, usually from the patient's stool, and identified as serotype 0157 by immunologic tests.
- Most E. coli 0157:H7 infections resolve s...
NegGram Caplets
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NegGram® Caplets
(nalidixic acid, USP)
To reduce the development of drug-resistant bacteria and maintain the effectiveness of NegGram (nalidixic acid, USP) and other antibacterial drugs, NegGram should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
DRUG DESCRIPTION
NegGram, brand of nalidixic acid, is a quinolone antibacterial agent for oral administration. Nalidixic acid is 1-ethyl-1, 4-dihydro-7-methyl-4-oxo-1, 8-naphthyridine-3-carboxylic acid. It is a pale yellow, crystalline substance and a very weak organic acid.
Nalidixic acid has the following structural formula:
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Inactive Ingredients - Hydrogenated Vegetable Oil, Methylcellulose, Microcrystalline Cellulose, Sodium Lauryl Sulfate, Yellow Ferric Oxide.
Last reviewed on RxList: 6/10/2011
This monograph has been modified to include the generic and brand name in many instances.
Next: Drug Description
Additional NegGram Caplets Information
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