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Neggram

Urinary tract infection (UTI) facts

  • Urinary tract infections (UTIs) are infections of the urethra, bladder, ureters, or the kidneys, which comprise the urinary tract.
  • E. coli bacteria cause the majority of UTIs, but many other bacteria, fungi, and parasites may also cause UTIs.
  • Females have a higher risk for UTIs than most males, probably because of their anatomy; other risk factors for UTIs include any condition that may impede urine flow (e.g., enlarged prostate, congenital urinary tract abnormalities, and inflammation). Patients with catheters or those who undergo urinary surgery and men with enlarged prostates are at higher risk for UTIs.
  • Symptoms and signs of UTI vary somewhat depending on sex, age, and the area of the urinary tract that is infected; some unique symptoms develop depending on the infecting agent.
  • UTIs are diagnosed usually by isolating and identifying the urinary pathogen from the patient; there a...

NegGram

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NegGram® Suspension
(nalidixic acid, USP) Oral Suspension

To reduce the development of drug-resistant bacteria and maintain the effectiveness of NegGram (nalidixic acid, USP) and other antibacterial drugs, NegGram should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

DRUG DESCRIPTION

NegGram, brand of nalidixic acid, is a quinolone antibacterial agent for oral administration. Nalidixic acid is 1-ethyl-1, 4-dihydro-7-methyl-4-oxo-1, 8-naphthyridine-3-carboxylic acid. It is a pale yellow, crystalline substance and a very weak organic acid.

Nalidixic acid has the following structural formula:

NegGram®  (nalidixic acid, USP) Structural Formula Illustration

Inactive Ingredients

Carbomere 934P, FD&C Red #40, Flavor, Parabens, Purified Water, Saccharin Sodium, Sodium Chloride, Sorbitol Solution.

Last reviewed on RxList: 6/10/2011
This monograph has been modified to include the generic and brand name in many instances.

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