"A class of medications long used to curb HIV infection shows promise as a therapy for age-related macular degeneration (AMD), suggest findings from an NIH-funded study. These mainstay HIV drugs, called nucleoside reverse transcriptase inhibitors "...
Ocular steroids are indicated in inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe where the inherent risk of steroid use in certain infective conjunctivitides is accepted to obtain a diminution in edema and inflammation. They are also indicated in chronic anterior uveitis and corneal injury from chemical, radiation, or thermal burns, or penetration of foreign bodies.
The use of a combination drug with an anti-infective component is indicated where the risk of infection is high or where there is an expectation that potentially dangerous numbers of bacteria will be present in the eye.
The particular anti-infective drug in this product is active against the following common bacterial eye pathogens:
The product does not provide adequate coverage against:
DOSAGE AND ADMINISTRATION
Instill one or two drops of Ophthalmic Solution NEODECADRON (neomycin and dexamethasone) into the conjunctival sac every hour during the day and every two hours during the night as initial therapy. When a favorable response is observed, reduce dosage to one drop every four hours. Later, further reduction in dosage to one drop three or four times daily may suffice to control symptoms.
Not more than 20 milliliters should be prescribed initially and the prescription should not be refilled without further evaluation as outlined in PRECAUTIONS above.
Sterile Ophthalmic Solution NEODECADRON (neomycin and dexamethasone) is a clear, colorless to pale yellow solution.
No. 7639 — Ophthalmic Solution NEODECADRON (neomycin and dexamethasone) is supplied as follows:
NDC 0006-7639-03 in 5 mL white opaque, plastic OCUMETER ophthalmic dispenser with a controlled drop tip.
(6505-01-039-4352 0.1% 5 mL).
Store at controlled room temperature, 15°-30°C (59°-86°F). Protect from light.
Distributed by: MERCK & CO., INC., West Point, PA 19486, USA. Issued December 1995.
Last reviewed on RxList: 2/24/2009
This monograph has been modified to include the generic and brand name in many instances.
Additional Neodecadron Information
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