Neostigmine Methylsulfate

Drug Description
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Neostigmine Methylsulfate
Injection, USP

DRUG DESCRIPTION

Neostigmine Methylsulfate Injection, USP is the dimethylcarbamate of (m-hydroxyphenyl) trimethylammonium methylsulfate.

The structural formula is:

Neostigmine Methylsulfate Structural Formula Illustration

C13H22N2O6S............................Molecular Weight 334.40

Neostigmine Methylsulfate, an anticholinesterase agent, is a bitter tasting, white crystalline powder and is very soluble in water and soluble in alcohol. Neostigmine Methylsulfate Injection, USP is a sterile, nonpyrogenic solution intended for intramuscular, subcutaneous or slow intravenous use.

Each mL of the 1:1000 concentration contains Neostigmine Methylsulfate 1 mg, Methylparaben 1.8 mg and Propylparaben 0.2 mg (used as preservatives), in Water for Injection q.s.pH (range 5.0 - 6.5) adjusted, when necessary, with Sodium Hydroxide.

Each mL of the 1:2000 concentration contains Neostigmine Methylsulfate 0.5 mg, Methylparaben 1.8 mg and Propylparaben 0.2 mg (used as preservatives), in Water for Injection q.s.pH (range 5.0 - 6.5) adjusted, when necessary, with Sodium Hydroxide.

Last updated on RxList: 6/26/2008


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