"The U.S. Food and Drug Administration today approved Bridion (sugammadex) injection to reverse the effects of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide, which are used during certain types of surgery in adu"...
Neostigmine Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Neostigmine methylsulfate injection is an anticholinesterase agent used to treat myasthenia gravis, postoperative distention and urinary retention, and to reverse effects of non-depolarizing neuromuscular blocking agents after surgery. Common side effects of neostigmine methylsulfate include salivation, increased mucus, muscle twitching, bowel or abdominal cramps, nausea, vomiting, diarrhea, decreased pupil size, increased urination, or increased sweating.
Dosage of neostigmine methylsulfate injection depends on the condition being treated. Neostigmine methylsulfate injection may interact with muscle relaxants, antibiotics, local and some general anesthetics, or antiarrhythmics. Tell your doctor all medications and supplements you use. During pregnancy, neostigmine methylsulfate injection should be used only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.
Our neostigmine methylsulfate injection Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Neostigmine FDA Prescribing Information: Side Effects
The following additional adverse reactions have been reported following the use of either Neostigmine Bromide or Neostigmine Methylsulfate (neostigmine methylsulfate (neostigmine methylsulfate injection) injection) .
Allergic: Allergic reactions and anaphylaxis.
Cardiovascular: Cardiac arrhythmias (including bradycardia, tachycardia, A-V block and nodal rhythm) and nonspecific EKG changes have been reported, as well as cardiac arrest, syncope and hypotension.These have been predominantly noted following the use of the injectable form of Neostigmine Methylsulfate (neostigmine methylsulfate (neostigmine methylsulfate injection) injection) .
Genitourinary: Urinary frequency.
Miscellaneous: Diaphoresis, flushing and weakness.
Read the entire FDA prescribing information for Neostigmine (Neostigmine Methylsulfate Injection)
Additional Neostigmine Methylsulfate Information
- Neostigmine Methylsulfate Drug Interactions Center: neostigmine methylsulfate inj
- Neostigmine Methylsulfate Side Effects Center
- Neostigmine Methylsulfate FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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