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Nesacaine®
(chloroprocaine HCl) Injection, USP
Nesacaine®-MPF
(chloroprocaine HCl) Injection, USP
For Infiltration and Nerve Block
Nesacaine (chloroprocaine) and Nesacaine (chloroprocaine) -MPF Injections are sterile non pyrogenic local anesthetics. The active ingredient in Nesacaine and Nesacaine-MPF Injections is chloroprocaine HCl (benzoic acid, 4-amino-2-chloro-2-(diethylamino) ethyl ester, monohydrochloride), which is represented by the following structural formula:
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Table 1: Composition of Available Injections
| Formula (mg/mL) | ||||
| Product Identification | Chloro-procaine HCl | Sodium Chloride | Disodium EDTA dihydrate | Methylparaben |
| Nesacaine 1% | 10 | 6.7 | 0.111 | 1 |
| Nesacaine 2% | 20 | 4.7 | 0.111 | 1 |
| Nesacaine-MPF 2% | 20 | 4.7 | - | - |
| Nesacaine-MPF 3% | 30 | 3.3 | - | - |
The solutions are adjusted to pH 2.7–4.0 by means of sodium hydroxide and/or hydrochloric acid. Filled under nitrogen. Nesacaine (chloroprocaine) and Nesacaine (chloroprocaine) -MPF Injections should not be resterilized by autoclaving.
Last reviewed on RxList: 3/9/2010
This monograph has been modified to include the generic and brand name in many instances.
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