Neupogen (Filgrastim) Patient Information: Side Effects and Drug Images at RxList

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May 27, 2012

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Hepatitis C infection facts

HCV is one of several viruses that cause hepatitis (inflammation of the liver).
Up to 85% of individuals who are initially (acutely) infected with HCV will fail to eliminate the virus and will become chronically infected.
HCV is spread most commonly through inadvertent exposure to infected blood. Intravenous drug abuse is the most common mode of transmission. The risk of acquiring HCV through sexual contact is low.
Generally, patients do not develop symptoms of chronic infection with HCV until they have extensive scarring of the liver (cirrhosis). Some individuals, however, may have fatigue and other non-specific symptoms in the absence of cirrhosis. A minority of patients with HCV have symptoms from organs outside of the liver.
In the U.S., Infection with HCV is the most common cause of chronic hepatitis and the most common reason for liver transplantation.
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Neupogen Patient Information Including Side Effects

Brand Names: Neupogen

Generic Name: filgrastim (Pronunciation: fil GRAS tim)

What is filgrastim (Neupogen)?

Filgrastim is a man-made form of a protein that stimulates the growth of white blood cells in your body. White blood cells help your body fight against infection.

Filgrastim is used to treat neutropenia, a lack of certain white blood cells caused by cancer, bone marrow transplant, receiving chemotherapy, or by other conditions.

Filgrastim may also be used for other purposes not listed in this medication guide.

What are the possible side effects of filgrastim (Neupogen)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using filgrastim and call your doctor at once if you have any of these serious side effects:

sudden or severe pain in your left upper stomach spreading up to your shoulder;
rapid breathing or feeling short of breath; or
signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or bleeding (nosebleeds, bleeding gums), loss of appetite, nausea and vomiting, mouth sores, unusual weakness.

Less serious side effects may include:

diarrhea, constipation;
bone pain;
muscle aches;
hair loss;
headache, tired feeling;
mild skin rash; or
itching, swelling, or redness where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about filgrastim (Neupogen)?

Before using filgrastim, tell your doctor if you have sickle cell disorder, a blood cell disorder, chronic myeloid leukemia, myelodysplasia (also called "preleukemia"), or if you are receiving chemotherapy or radiation treatment.

Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of needles, IV tubing, and other items used in giving the medicine.

Filgrastim is usually given daily for up to 2 weeks. Follow your doctor's instructions. For best results, use this medication at the same time each day.

To be sure this medication is helping your condition, your blood will need to be tested often. This will help your doctor determine how long to treat you with filgrastim. Your liver function will also need to be tested. Do not miss any scheduled appointments.

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