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Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Neupro Patient Information Including Side Effects

Brand Names: Neupro

Generic Name: rotigotine (transdermal) (Pronunciation: roe TIG oh teen)

What is rotigotine (Neupro)?

Rotigotine has some of the same effects as a chemical called dopamine, which occurs naturally in your body. Low levels of dopamine in the brain are associated with Parkinson's disease.

Rotigotine is used to treat early signs and symptoms of Parkinson's disease.

Rotigotine may also be used for purposes other than those listed in this medication guide.

Rotigotine skin patches were withdrawn from the U.S. market in April 2008.

What are the possible side effects of rotigotine (Neupro)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • extreme drowsiness, falling asleep suddenly, even after feeling alert;
  • nausea, sweating, feeling light-headed, fainting;
  • breathing problems;
  • severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure;
  • hallucinations;
  • swelling in your hands or feet; or
  • restless muscle movements in your eyes, tongue, jaw, or neck.

Less serious side effects may include:

  • weight gain;
  • swelling, redness, or itching where the patch was applied.
  • urinating more than usual;
  • runny nose;
  • diarrhea, loss of appetite;
  • feeling dizzy, tired, or weak;
  • mild drowsiness or sleepiness;
  • headache;
  • sleep problems (insomnia);
  • blurred vision; or
  • swelling in your hands or feet.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the Neupro (rotigotine transdermal system) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about rotigotine (Neupro)?

Rotigotine skin patches were withdrawn from the U.S. market in April 2008.

Do not stop using rotigotine without first talking to your doctor. You may need to use less and less before you stop using the patches completely. Stopping suddenly can cause fever, stiff muscles, confusion, sweating, and fast or uneven heartbeats.

Rotigotine may cause you to fall asleep during normal daytime activities such as working, talking, eating, or driving. You may fall asleep suddenly, even after feeling alert. Tell your doctor if you have any problems with daytime sleepiness or drowsiness. If you are unsure of how this medicine will affect you, be careful if you drive or do anything that requires you to be awake and alert.

Call your doctor at once if you have serious side effects such as extreme drowsiness, falling asleep suddenly, breathing problems, severe or sudden headache, hallucinations, chest pain, swelling, fainting, or restless muscle movements in your eyes, tongue, jaw, or neck.

You may have increased sexual urges, intense or unusual urges to gamble, or other intense urges while taking rotigotine. Talk with your doctor if you believe you have any intense or unusual urges while you are using rotigotine.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

The rotigotine transdermal patch may burn your skin if you wear the patch during an MRI (magnetic resonance imaging). Remove the patch before undergoing such a test.

Side Effects Centers

Neupro - User Reviews

Neupro User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Neupro sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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