Neutrexin
Breath Test May Detect Colon Cancer »
"Dec. 5, 2012 -- A breath test similar to the one used to determine when a driver has had too much to drink shows promise as a screening tool for cancer.
In a new study from Italy, researchers were able to identify patients with colorectal c"...
Neutrexin
Please Note: This Brand Name drug is no longer available in the US.(Generic versions may still be available.)
OVERDOSE
Neutrexin (trimetrexate glucuronate for injection) administered without concurrent leucovorin can cause lethal complications. There has been no extensive experience in humans receiving single intravenous doses of trimetrexate greater than 90 mg/m2/day with concurrent leucovorin. The toxicities seen at this dose were primarily hematologic. In the event of overdose, Neutrexin (trimetrexate glucuronate inj) should be stopped and leucovorin should be administered at a dose of 40 mg/m2 every 6 hours for 3 days. The LD50 of intravenous trimetrexate in mice is 62 mg/kg (186 mg/m2).
CONTRAINDICATIONS
Neutrexin (trimetrexate glucuronate for injection) is contraindicated in patients with clinically significant sensitivity to trimetrexate, leucovorin, or methotrexate.
Last reviewed on RxList: 4/20/2009
This monograph has been modified to include the generic and brand name in many instances.
Additional Neutrexin Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Cancer
Get the latest treatment options.
Updated & New
