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Nexavar

The kidneys

The kidneys are a pair of organs on either side of the spine in the lower abdomen. Each kidney is about the size of a fist. Attached to the top of each kidney is an adrenal gland. A mass of fatty tissue and an outer layer of fibrous tissue (Gerota's fascia) enclose the kidneys and adrenal glands.

The kidneys are part of the urinary tract. They make urine by removing wastes and extra water from the blood. Urine collects in a hollow space (renal pelvis) in the middle of each kidney. It passes from the renal pelvis into the bladder through a tube called a ureter. Urine leaves the body through another tube (the urethra).

The kidneys also make substances that help control blood pressure and the production of red blood cells.

Understanding cancer

Nexavar

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Nexavar Drug Center

Medical Editor: John P. Cunha, DO, FACOEP

Nexavar (sorafenib) is used to treat a type of kidney cancer called advanced renal cell carcinoma. It is also used to treat liver cancer. It is a cancer (chemotherapeutic) medication. Common side effects include acne, dry skin, nausea, diarrhea, patchy hair loss/thinning, loss of appetite, dry mouth, hoarseness, or tiredness.

The recommended daily dose of Nexavar is 400 mg (2 x 200 mg tablets) taken twice daily without food (at least 1 hour before or 2 hours after a meal). Nexavar may interact with warfarin, dexamethasone, rifampin, St. John's wort, seizure medication, or other cancer medications. Tell your doctor all medications and supplements you use. Nexavar is not recommended for use during pregnancy. It may harm a fetus. Men and women must use birth control during treatment and for at least 2 weeks after stopping this drug. Consult your doctor. It is unknown if this drug passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this drug is not recommended.

Our Nexavar (sorafenib) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Nexavar Prescribing Information: Indications & Dosage

NEXAVAR (sorafenib)  Structural Formula Illustration

Hepatocellular Carcinoma

NEXAVAR® is indicated for the treatment of patients with unresectable hepatocellular carcinoma (HCC).

Renal Cell Carcinoma

NEXAVAR is indicated for the treatment of patients with advanced renal cell carcinoma (RCC).

Read the complete drug monograph for Nexavar »

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Nexavar Patient Information: Side Effects

Stop using sorafenib and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • rash, blisters, oozing, or severe pain in the palms of your hands or the soles of your feet;
  • increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);
  • easy bruising, unusual bleeding;
  • black, bloody, or tarry stools;
  • ...

Read the complete patient information for Nexavar »

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Nexavar Consumer Information: Uses

This medication is used to treat kidney or liver cancer. Sorafenib stops or slows the growth of cancer cells (tumors). It also works by slowing the growth of new blood vessels within the tumor.

HOW TO USE: Read the Patient Information Leaflet provided by your pharmacist before you start using sorafenib and each time you get a refill. If you have any questions, consult your doctor or pharmacist.

Take this medication by mouth on an empty stomach (at least 1 hour before or 2 hours after a meal) as directed by your doctor. Do not chew or crush the ta...

Read the complete consumer information for Nexavar »

What is Nexavar Consumer Information?

Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More

Nexavar - User Reviews

Nexavar User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Nexavar sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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