"The U.S. Food and Drug Administration approved the cancer drug Afinitor (everolimus) on Friday to treat patients with subependymal giant cell astrocytoma (SEGA) associated with tuberous sclerosis (TS), a rare genetic disorder. This approval was f"...
Nexavar Patient Information including If I Miss a Dose
In this Article
- What is sorafenib (Nexavar)?
- What are the possible side effects of sorafenib (Nexavar)?
- What is the most important information I should know about sorafenib (Nexavar)?
- What should I discuss with my health care provider before taking sorafenib (Nexavar)?
- How should I take sorafenib (Nexavar)?
- What happens if I miss a dose (Nexavar)?
- What happens if I overdose (Nexavar)?
- What should I avoid while taking sorafenib (Nexavar)?
- What other drugs will affect sorafenib (Nexavar)?
- Where can I get more information?
What happens if I miss a dose (Nexavar)?
Take the missed dose as soon as you remember, but at least 2 hours since your last meal. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Nexavar)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include severe diarrhea or severe skin rash.
What should I avoid while taking sorafenib (Nexavar)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
What other drugs will affect sorafenib (Nexavar)?
Tell your doctor about all other cancer medicines you use, especially cyclophosphamide (Cytoxan, Neosar), docetaxel (Taxotere), doxorubicin (Adriamycin, Rubex), fluorouracil (Adrucil, Carac, Efudex, Fluoroplex), irinotecan (Camptosar), paclitaxel (Taxol) or tamoxifen (Soltamox).
The following drugs can interact with sorafenib. Tell your doctor if you are using any of these:
- a blood thinner such as warfarin (Coumadin);
- bosentan (Tracleer);
- dexamethasone (Decadron, Hexadrol);
- montelukast (Singulair) or zafirlukast (Accolate);
- neomycin (Mycifradin, Neo Fradin, Neo Tab);
- promethazine (Phenergan, Adgan, Anergan, Antinaus, Pentazine);
- rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), or rifapentine (Priftin);
- selegiline (Eldepryl, Emsam, Zelapar);
- St. John's wort;
- voriconazole (Vfend);
- an antidepressant such as bupropion (Wellbutrin), fluoxetine (Prozac);
- a barbiturate such as butabarbital (Butisol), secobarbital (Seconal), pentobarbital (Nembutal);
- heart or blood pressure medications such as amiodarone (Cordarone, Pacerone), carvedilol (Coreg), losartan (Hyzaar, Cozaar), or torsemide (Demadex);
- HIV medication such as efavirenz (Sustiva), etravirine (Intelence), nevirapine (Viramune), or ritonavir (Norvir);
- medicines to treat narcolepsy, such as armodafanil (Nuvigil) or modafanil (Progivil);
- seizure medication such as carbamazepine (Carbatrol, Equetro, Tegretol), felbamate (Felbatol), fosphenytoin (Cerebyx), oxcarbazepine (Trileptal), phenytoin (Dilantin), phenobarbital (Luminal, Solfoton), or primidone (Mysoline);
- sulfa drugs (Bactrim, Gantanol, Gantrisin, Septra, SMX-TMP, and others); or
- type 2 diabetes medications such as glimepiride (Amaryl), glipizide (Glucotrol), nateglinide (Starlix), pioglitazone (Actos, Actoplus Met), repaglinide (Prandin), rosiglitazone (Avandia, Avandamet), or tolbutamide (Orinase).
This list is not complete and other drugs may interact with sorafenib. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about sorafenib.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 4.01. Revision date: 5/27/2011.
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Additional Nexavar Information
- Nexavar Drug Interactions Center: sorafenib oral
- Nexavar Side Effects Center
- Nexavar Overview including Precautions
- Nexavar FDA Approved Prescribing Information including Dosage
Nexavar - User Reviews
Nexavar User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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