Nexavar (Sorafenib) Patient Information: How Should I Take the Drug at RxList

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May 27, 2012

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Kidney Cancer »

The kidneys

The kidneys are a pair of organs on either side of the spine in the lower abdomen. Each kidney is about the size of a fist. Attached to the top of each kidney is an adrenal gland. A mass of fatty tissue and an outer layer of fibrous tissue (Gerota's fascia) enclose the kidneys and adrenal glands.

The kidneys are part of the urinary tract. They make urine by removing wastes and extra water from the blood. Urine collects in a hollow space (renal pelvis) in the middle of each kidney. It passes from the renal pelvis into the bladder through a tube called a ureter. Urine leaves the body through another tube (the urethra).

The kidneys also make substances that help control blood pressure and the production of red blood cells.

Understanding cancer

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Nexavar Patient Information including How Should I Take

What should I discuss with my health care provider before taking sorafenib (Nexavar)?

Do not use this medication if you are allergic to sorafenib.

Before using this medication, tell your doctor if you are allergic to any drugs, or if you have:

kidney or liver disease;
a bleeding or blood clotting disorder such as hemophilia;
high blood pressure (hypertension);
heart disease; or
a history of stroke or heart attack.

If you have any of the conditions listed above, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category D. This medication can cause harm to an unborn baby. Do not use this medication if you are pregnant. Tell your doctor if you become pregnant during treatment. Both men and women taking sorafenib should use an effective form of birth control while taking the medication and for at least 2 weeks after treatment ends.

It is not known whether sorafenib passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take sorafenib (Nexavar)?

Take this medicine exactly as your doctor has prescribed it for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take sorafenib on an empty stomach, at least 1 hour before or 2 hours after eating.

Swallow the tablet whole with a glass of water.

To be sure this medication is not causing harmful side effects, your blood pressure will need to be checked on a regular basis. Do not miss any scheduled visits to your doctor.

If you need to have any type of surgery, tell the surgeon ahead of time that you are using sorafenib. You may need to stop using the medicine for a short time.

Store sorafenib at room temperature away from moisture and heat.

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