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Nexavar Patient Information Including Side Effects
Brand Names: Nexavar
Generic Name: sorafenib (Pronunciation: sor a FEN ib)
- What is sorafenib (Nexavar)?
- What are the possible side effects of sorafenib (Nexavar)?
- What is the most important information I should know about sorafenib (Nexavar)?
- What should I discuss with my health care provider before taking sorafenib (Nexavar)?
- How should I take sorafenib (Nexavar)?
- What happens if I miss a dose (Nexavar)?
- What happens if I overdose (Nexavar)?
- What should I avoid while taking sorafenib (Nexavar)?
- What other drugs will affect sorafenib (Nexavar)?
- Where can I get more information?
What is sorafenib (Nexavar)?
Sorafenib is a cancer medication that interferes with the growth and spread of cancer cells in the body.
Sorafenib is used to treat a type of kidney cancer called advanced renal cell carcinoma. It is also used to treat liver cancer.
Sorafenib may also be used for purposes not listed in this medication guide.
What are the possible side effects of sorafenib (Nexavar)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using sorafenib and call your doctor at once if you have a serious side effect such as:
- rash, blisters, oozing, or severe pain in the palms of your hands or the soles of your feet;
- mouth sores;
- black or bloody stools, coughing up blood or vomit that looks like coffee grounds;
- pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
- easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
- chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
- dry cough, wheezing;
- swelling, rapid weight gain, feeling short of breath (even with mild exertion);
- sudden numbness or weakness, especially on one side of the body;
- upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- sudden weight loss, increased appetite, trouble sleeping, increased bowel movements, feeling hot, feeling nervous or anxious, swelling in your neck (goiter);
- dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, confusion, uneven heartbeats, seizure); or
- severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Less serious side effects may include:
- tired feeling;
- vomiting, diarrhea, mild stomach pain;
- mild itching or rash; or
- thinning hair.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the Nexavar (sorafenib) Side Effects Center for a complete guide to possible side effects
What is the most important information I should know about sorafenib (Nexavar)?
Do not use sorafenib if you are pregnant. It could harm the unborn baby. Use effective birth control while you are using this medication and for at least 2 weeks after your treatment ends, whether you are a man or a woman. Sorafenib use by either parent may cause birth defects.
Do not breast-feed while using this medication.
You should not use sorafenib if you are allergic to it, or if you have squamous cell lung cancer and you are being treated with carboplatin (Paraplatin) and paclitaxel (Onxol, Taxol, Abraxane).
Before you take sorafenib, tell your doctor if you have kidney or liver problems (other than cancer), a bleeding or blood clotting disorder, high blood pressure, heart disease, slow heartbeats, congestive heart failure, a personal or family history of Long QT syndrome, a history of stroke or heart attack, or any allergies.
There are many other drugs that can interact with sorafenib. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
If you need surgery or dental work, tell the surgeon or dentist ahead of time that you are taking sorafenib.
Additional Nexavar Information
- Nexavar Drug Interactions Center: sorafenib oral
- Nexavar Side Effects Center
- Nexavar Overview including Precautions
- Nexavar FDA Approved Prescribing Information including Dosage
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