Nexium I.V. (Esomeprazole Sodium) Drug Information: Medication Guide and Patient Information

May 27, 2012

Peptic ulcers are sores in the lining of the stomach or duodenum.
Peptic ulcer formation is related to H. pylori bacteria in the stomach and nonsteroidal anti-inflammatory medications (NSAIDs) in 50% of patients. For the remaining 50% there are miscellaneous or unknown causes.
Ulcer pain may not correlate with the presence or severity of ulceration.
The main symptom of peptic ulcer is upper abdominal pain which can be dull, sharp, or burning. (Bloating and burping are not symptoms of peptic ulcer, and vomiting, poor appetite, and nausea are uncommon symptoms of peptic ulcer.)
Diagnosis of ulcer is made with upper GI series or endoscopy.
Treatment of ulcers involves antibiotic combinations along with stomach acid suppression to eradicate H. pylori, eliminating precipitating factors such as NSAIDs and stomach acid suppression...

Nexium I.V.

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Advise patients to let their healthcare provider know if they are taking, or begin taking other medications, because NEXIUM can interfere with antiretroviral drugs and drugs that are affected by gastric pH changes [see DRUG INTERACTIONS].
Let patients know that antacids may be used while taking NEXIUM.

Advise patients to immediately report and seek care for any cardiovascular or neurological symptoms including palpitations, dizziness, seizures, and tetany as these may be signs of hypomagnesemia [see WARNINGS AND PRECAUTIONS].

Last reviewed on RxList: 2/3/2012
This monograph has been modified to include the generic and brand name in many instances.