July 23, 2016

Nickel

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How does Nickel work?

Nickel is an essential nutrient in some chemical processes in the body. Its precise functions in the body are not known.

Are there safety concerns?

Nickel is LIKELY SAFE for most adults when taken by mouth in amounts up to 1 mg/day. Taking more than 1 mg/day is POSSIBLY UNSAFE. Taking amounts slightly above the 1 mg/day level increases the chances of unwanted side effects. High doses are poisonous.

Workers who have been exposed to nickel on the job over an extended period of time can develop allergies, lung disorders, and cancer.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Nickel is LIKELY SAFE in pregnant or breast-feeding adult women when taken by mouth in doses less than the tolerable upper intake level (UL) of 1 mg/day. The safety of higher doses is unknown.

Children: Nickel is LIKELY SAFE in children in daily doses less than the tolerable upper intake level (UL) of 0.2 mg/day in children 1 to 3 years, 0.3 mg/day in children 4 to 8 years, and 0.6 mg/day in children 9 to 13 years. Taking higher doses is POSSIBLY UNSAFE.

Kidney disease: People with kidney disease may not be able to tolerate nickel as well as other people. It's best to avoid nickel supplements if you have kidney problems.

Nickel allergy: People who are sensitive to nickel, including those with a history of skin rash after contact with nickel-containing jewelry, coins, stainless steel items, surgical implants, or dental appliances, can develop allergic reactions to nickel taken by mouth. These people should not take nickel supplements.


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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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