"Increased use of prescription opioids during pregnancy is likely a contributing factor in the rise in rates of neonatal abstinence syndrome (NAS) in the United States, warns Nora D. Volkow, MD, director of the National Institute on Drug Abuse (NI"...
The clinical course of acute iron overdosage can be variable. Initial symptoms may include abdominal pain, nausea, vomiting, diarrhea, tarry stools, melena, hematemesis, hypotension, tachycardia, metabolic acidosis, hyperglycemia, dehydration, drowsiness, pallor, cyanosis, lassitude, seizures, shock and coma.
The oral LD50 of polysaccharide iron complex was estimated to be greater than 5000 mg iron/kg in the rat. Chronic toxicity studies in rats and dogs administered polysaccharide iron complex showed that a daily dosage of 250 mg iron/kg for three months had no adverse effects.
Niferex®-150 Forte is contraindicated in patients with a known hypersensitivity to any of the components of this product. Hemochromatosis and hemosiderosis are contraindications to iron therapy.This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 8/15/2008
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