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Nitroprusside is a vasodilator that works by relaxing the muscles in your blood vessels to help them dilate (widen). This lowers blood pressure and allows blood to flow more easily through your veins and arteries.
Nitroprusside is used to treat congestive heart failure and life-threatening high blood pressure (hypertension). Nitroprusside is also used to keep blood pressure low during a surgery.
Nitroprusside may also be used for purposes other than those listed in this medication guide.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers at once if you have any of these serious side effects:
Less serious side effects may be more likely to occur, such as:
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
You should not receive this medication if you are allergic to nitroprusside, or if you have hereditary vision loss (Leber's disease), vision problems caused by smoking, or a history of blood clot in your brain.
Before receiving nitroprusside, tell your doctor if you have high blood pressure (hypertension), liver disease, anemia (a lack of red blood cells), a seizure disorder, or a history of head injury or brain tumor.
Seek emergency medical attention if you think you have received too much of this medicine.
Symptoms of a nitroprusside overdose may include nausea, vomiting, stomach pain, sweating, severe dizziness, headache, muscle twitching, fast or pounding heartbeat, restless feeling, and chest or back pain.
Tell your caregivers right away about any serious side effects such as breathing problems, tremors or chills, numbness or cold feeling in your hands or feet, easy bruising, unusual bleeding, muscle pain or weakness, confusion, feeling extremely light-headed, or fainting.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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