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Nitrostat

What is Raynaud's phenomenon?

Raynaud's phenomenon (RP) is a condition resulting in a particular series of discolorations of the fingers and/or the toes after exposure to changes in temperature (cold or hot) or emotional events. Skin discoloration occurs because an abnormal spasm of the blood vessels causes a diminished blood supply to the local tissues. Initially, the digit(s) involved turn white because of the diminished blood supply. The digit(s) then turn blue because of prolonged lack of oxygen. Finally, the blood vessels reopen, causing a local "flushing" phenomenon, which turns the digit(s) red. This three-phase color sequence (white to blue to red), most often upon exposure to cold temperature, is characteristic of RP.

Raynaud's phenomenon most frequently affects women, especially in the second, third, or fourth decades of life. People can have Raynauds phenomenon alone or as a part of other rheumatic diseases. When it occurs alone...

Nitrostat

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Nitrostat®
(nitroglycerin) Sublingual Tablets, USP

DRUG DESCRIPTION

NITROSTAT is a stabilized sublingual compressed nitroglycerin tablet that contains 0.3 mg, 0.4 mg , or 0.6 mg nitroglycerin; as well as lactose monohydrate, NF; glyceryl monostearate, NF; pregelatinized starch, NF; calcium stearate, NF powder; and silicon dioxide, colloidal, NF.

Nitroglycerin, an organic nitrate, is a vasodilating agent. The chemical name for nitroglycerin is 1, 2, 3 propanetriol trinitrate and the chemical structure is:

Nitrostat® (Nitroglycerin) Structural Formula Illustration

Molecular weight: 227.09

What are the possible side effects of nitroglycerin (Nitrolingual, Nitrolingual Duo Pack, Nitroquick, Nitrostat)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • fast, slow, pounding, or uneven heart rate;
  • blurred vision or dry mouth;
  • nausea, vomiting, sweating, pale skin, feeling like you might pass out; or
  • fever, sore throat, and headache with a severe blistering,...

Read All Potential Side Effects and See Pictures of Nitrostat »

What are the precautions when taking nitroglycerin (Nitrostat)?

Before using this medication, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such as isosorbide mononitrate); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: recent head injury, frequent stomach cramping/watery stools/severe diarrhea (GI hypermotility), lack of proper absorption of nutrients (malabsorption).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: anemia, low blood pressure, loss of too much body water...

Read All Potential Precautions of Nitrostat »

Last reviewed on RxList: 8/5/2011
This monograph has been modified to include the generic and brand name in many instances.

Nitrostat - User Reviews

Nitrostat User Reviews

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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