Nitroglycerin is indicated for the acute relief of an attack or acute prophylaxis of angina pectoris due to coronary artery disease.

One tablet should be dissolved under the tongue or in the buccal pouch at the first sign of an acute anginal attack. The dose may be repeated approximately every 5 minutes until relief is obtained. If the pain persists after a total of 3 tablets in a 15-minute period, or if the pain is different than is typically experienced, prompt medical attention is recommended. NITROSTAT may be used prophylactically 5 to 10 minutes prior to engaging in activities that might precipitate an acute attack.

During administration the patient should rest, preferably in the sitting position.

No dosage adjustment is required in patients with renal failure.

NITROSTAT is supplied as white, round, flat-faced tablets in 3 strengths (0.3 mg,

0.4 mg, and 0.6 mg) in bottles containing 100 tablets each, with color-coded labels, and in color-coded Patient Convenience Packages of 4 bottles of 25 tablets each.

0.3 mg: Coded “N” on one side and “3” on the other.
NDC 0071-0417-24—Bottle of 100 tablets

0.4 mg: Coded “N” on one side and “4” on the other.
NDC 0071-0418-13—Convenience Package
NDC 0071-0418-24—Bottle of 100 tablets

0.6 mg: Coded “N” on one side and “6” on the other.
NDC 0071-0419-24—Bottle of 100 tablets

Store at Controlled Room Temperature 20°–25°C (68°–77°F) [see USP].

Distributed by: Parke-Davis, Division of Pfizer Inc., NY, NY 10017. Revised May 2011

Last reviewed on RxList: 8/5/2011
This monograph has been modified to include the generic and brand name in many instances.