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Chloral hydrate is indicated for nocturnal sedation in all types of patients and especially for the ill, the young, and the elderly patient.
In candidates for surgery, it is a satisfactory preoperative sedative that allays anxiety and induces sleep without depressing respiration or cough reflex. In postoperative care and control of pain, it is a valuable adjunct to opiates and analgesics.
DOSAGE AND ADMINISTRATION
The syrup may be administered in a half glass of water, fruit juice, or ginger ale.
The usual hypnotic dose is 500 mg to 1 g, taken 15 to 30 minutes before bedtime or ½ hour before surgery. The usual sedative dose is 250 mg three times daily after meals. Generally, single doses or daily dosage should not exceed 2 g.
The usual daily hypnotic dose is 50 mg/ kg of body weight, with a maximum of 1 g per single dose. Daily dosage may be given in divided doses if indicated. The sedative dose is half of the hypnotic dosage.
Chloral Hydrate Syrup, USP is supplied as a clear, pink to orange colored, orange flavored syrup containing 500 mg (7½ gr) in 5 mL (teaspoonful) in the following size:
16 fl oz (473 mL)
Store at controlled room temperature, 15°-30° C (59°-86° F).
AVOID EXCESSIVE HEAT
Dispense in tight, light- resistant containers as defined in the USP.
CAUTION: Federal law prohibits dispensing without prescription.
Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.
Additional Noctec Information
- Noctec Drug Interactions Center: chloral hydrate oral
- Noctec Side Effects Center
- Noctec Overview including Precautions
- Noctec FDA Approved Prescribing Information including Dosage
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