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Chloral hydrate is indicated for nocturnal sedation in all types of patients and especially for the ill, the young, and the elderly patient.
In candidates for surgery, it is a satisfactory preoperative sedative that allays anxiety and induces sleep without depressing respiration or cough reflex. In postoperative care and control of pain, it is a valuable adjunct to opiates and analgesics.
DOSAGE AND ADMINISTRATION
The syrup may be administered in a half glass of water, fruit juice, or ginger ale.
The usual hypnotic dose is 500 mg to 1 g, taken 15 to 30 minutes before bedtime or ½ hour before surgery. The usual sedative dose is 250 mg three times daily after meals. Generally, single doses or daily dosage should not exceed 2 g.
The usual daily hypnotic dose is 50 mg/ kg of body weight, with a maximum of 1 g per single dose. Daily dosage may be given in divided doses if indicated. The sedative dose is half of the hypnotic dosage.
Chloral Hydrate Syrup, USP is supplied as a clear, pink to orange colored, orange flavored syrup containing 500 mg (7½ gr) in 5 mL (teaspoonful) in the following size:
16 fl oz (473 mL)
Store at controlled room temperature, 15°-30° C (59°-86° F).
AVOID EXCESSIVE HEAT
Dispense in tight, light- resistant containers as defined in the USP.
CAUTION: Federal law prohibits dispensing without prescription.
Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.
Additional Noctec Information
- Noctec Drug Interactions Center: chloral hydrate oral
- Noctec Side Effects Center
- Noctec FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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