Norco 5/325 (Hydrocodone Bitartrate and Acetaminophen) Patient Information: Side Effects and Drug Images at RxList

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May 27, 2012

Norco 5-325

Liver Disease »

What is liver disease?

Liver disease is any disturbance of liver function that causes illness. The liver is responsible for many critical functions within the body and should it become diseased or injured, the loss of those functions can cause significant damage to the body. Liver disease is also referred to as hepatic disease.

Liver disease is a broad term that covers all the potential problems that may occur to cause the liver to fail to perform its designated functions. Usually, more than 75% or three quarters of liver tissue needs to be affected before decrease in function occurs.

The liver the largest solid organ in the body; and is also considered a gland because among its many functions, it makes and secretes bile. The liver is located in the upper right portion of the abdomen protected by the rib cage. It has two main lobes that are made up of tiny lobules. The liver cells have two different sources of blood supply. The hepatic ...

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NORCO® 5/325
Hydrocodone Bitartrate and Acetaminophen Tablets USP
5 mg/325 mg

DRUG DESCRIPTION

NORCO^®(Hydrocodone bitartrate and acetaminophen) is supplied in tablet form for oral administration.

Hydrocodone bitartrate is an opioid analgesic and antitussive and occurs as fine, white crystals or as a crystalline powder. It is affected by light. The chemical name is 4,5a-Epoxy-3-methoxy-17-methylmorphinan-6-one tartrate (1:1) hydrate (2:5). It has the following structural formula:

½ C₁₈H₂₁NO_3·C₄H₆O_6·2 ½ H₂O

M.W. = 494.49

Acetaminophen, 4´-Hydroxyacetanilide, a slightly bitter, white, odorless, crystalline powder, is a non-opiate, non-salicylate analgesic and antipyretic. It has the following structural formula:

C₈H₉NO₂

M.W. = 151.16

Each NORCO^® 5/325 tablet contains:

Hydrocodone Bitartrate......5 mg

Acetaminophen...............325 mg

In addition, each tablet contains the following inactive ingredients: colloidal silicon dioxide, croscarmellose sodium, crospovidone, microcrystalline cellulose, povidone, pregelatinized starch, stearic acid and sugar spheres which are composed of starch derived from corn, sucrose, and FD&C Yellow #6. Meets USP Dissolution Test 1.

Last reviewed on RxList: 3/24/2006
This monograph has been modified to include the generic and brand name in many instances.