Norco (Hydrocodone Bitartrate and Acetaminophen) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Norco

Lower Back Pain »

Low back pain facts

Functions of the low back, or lumbar area, include structural support, movement, and protection of certain body tissues.
Pain in the low back can relate to the bony lumbar spine, discs between the vertebrae, ligaments around the spine and discs, spinal cord and nerves, muscles of the low back, internal organs of the pelvis and abdomen, and the skin covering the lumbar area.
Treatment of low back pain is optimally directed toward a diagnosed or suspected specific cause. For acute lumbar strain, use of a home remedy initially can be beneficial.

What is the anatomy of the low back?

The first step to understanding low back pain is appreciating the normal design (anatomy) of the tissues of this area of the body. Important structures of the low back that can be related to symptoms in this region include the bony lumbar spine (vertebrae, singular = vert...

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NORCO® 7.5/325
(hydrocodone bitartrate and acetaminophen)
NORCO® 10/325
(hydrocodone bitartrate and acetaminophen) Tablet

DRUG DESCRIPTION

NORCO® (hydrocodone bitartrate and acetaminophen) is supplied in tablet form for oral administration.

Hydrocodone bitartrate is an opioid analgesic and antitussive and occurs as fine, white crystals or as a crystalline powder. It is affected by light. The chemical name is 4,5α-Epoxy-3-methoxy-17-methylmorphinan-6-one tartrate (1:1) hydrate (2:5). It has the following structural formula:

Hydrocodone bitartrate structural formula illustration

C₁₈H₂₁NO₃•C₄H₆O₆•2½H₂O M. W. = 494.49

Acetaminophen, 4´-Hydroxyacetanilide, a slightly bitter, white, odorless, crystalline powder, is a non-opiate, non-salicylate analgesic and antipyretic. It has the following structural formula:

Acetaminophen structural formula illustration

C₈H₉NO₂ M. W. = 151.16

NORCO (hydrocodone bitartrate and acetaminophen) ®, for oral administration is available in the following strengths:

	Hydrocodone Bitartrate	Acetaminophen
NORCO® 7.5/325	7.5 mg	325 mg
NORCO® 10/325	10 mg	325 mg

In addition, each tablet contains the following inactive ingredients: croscarmellose sodium, crospovidone, magnesium stearate, microcrystalline cellulose, povidone, pregelatinized starch, and stearic acid; the 7.5 mg/325 mg tablets include FD&C Yellow #6 Aluminum Lake, the 10 mg/325 mg tablets include D&C Yellow #10 Aluminum Lake. Meets USP Dissolution Test 1.

What are the precautions when taking hydrocodone bitartrate and acetaminophen (Norco)?

Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to other narcotics (such as morphine, codeine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: brain disorders (such as head injury, tumor, seizures), breathing problems (such as asthma, sleep apnea, chronic obstructive pulmonary disease-COPD), kidney disease, liver disease, mental/mood disorders (such as confusion, depression), personal or family history of regular use/abuse of drugs/alcohol, stomach/intestinal problems (such as blockage, constipation, diarrhea...

Read All Potential Precautions of Norco »

Last reviewed on RxList: 9/27/2010
This monograph has been modified to include the generic and brand name in many instances.