"Nov. 1, 2012 -- Two more drugs made by the New England Compounding Center (NECC) are crawling with various kinds of bacteria, FDA tests reveal.
The NECC is the Massachusetts compounding pharmacy whose drugs are the likely source of th"...
Norco Side Effects Center
Medical Editor: Charles Patrick Davis, MD, PhD
Norco (hydrocodone bitartrate and acetaminophen) is an opioid analgesic and antitussive (cough suppressant) that is combined with acetaminophen and used to treat moderate to fairly severe pain. All strengths of Norco are available as a generic combined with acetaminophen. The most frequent side effects of Norco are lightheadedness, nausea, vomiting, constipation, and sedation. When first taking Norco, the patient should not drive or do other tasks that require good concentration and focus to avoid harming themselves or others.
Norco is supplied in tablet forms with strengths of 7.5 or 10 mg of hydrocodone bitartrate combined with 325 mg of acetaminophen. The daily dose for both strengths is one tablet every 4 to 6 hours as needed for pain. No more than 6 tablets should be taken over 24 hours. Short treatment (less than a week) usually does not cause patient's to become dependent on the drug, develop tolerance, or develop an opioid withdrawal syndrome. Longer constant use may allow these serious side effects to develop. Some patients, especially if they exceed the recommended doses, can experience respiratory depression and death. Most medications that depress the central nervous system can enhance the effects of Norco (antihistamines, narcotics, anti-anxiety medications and alcohol); this enhancement may cause respiratory depression so doses of Norco. There are no studies that suggest Norco is safe to use in pregnancy or in pediatric patients; however, pregnant women taking Norco regularly will produce an infant likely to be opioid dependent and may have respiratory depression. Studies with lactating women taking Norco are lacking so the safety is at best, questionable. Although the above is written about Norco, readers should be aware that over 250 different drugs are available that have the same two (or more) combinations of drugs as Norco and thus have a similar drug profile.
Our Norco Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Norco in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- shallow breathing, slow heartbeat;
- feeling light-headed, fainting;
- confusion, fear, unusual thoughts or behavior;
- seizure (convulsions);
- problems with urination; or
- nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
- anxiety, dizziness, drowsiness;
- mild nausea, vomiting, upset stomach, constipation;
- headache, mood changes;
- blurred vision;
- ringing in your ears; or
- dry mouth.
Read the entire detailed patient monograph for Norco (Hydrocodone Bitartrate and Acetaminophen) »
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Norco Overview - Patient Information: Side Effects
Nausea, vomiting, constipation, lightheadedness, dizziness, or drowsiness may occur. Some of these side effects may decrease after you have been using this medication for a while. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
To prevent constipation, eat a diet adequate in fiber, drink plenty of water, and exercise. Consult your pharmacist for help in selecting a laxative (such as a stimulant type with stool softener).
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: mental/mood changes, severe stomach/abdominal pain, difficulty urinating.
Seek immediate medical attention if any of these rare but serious side effects occur: fainting, seizure, slow/shallow breathing, unusual drowsiness/difficulty waking up.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Norco (Hydrocodone Bitartrate and Acetaminophen)»
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Norco FDA Prescribing Information: Side Effects
The most frequently reported adverse reactions are lightheadedness, dizziness, sedation, nausea and vomiting. These effects seem to be more prominent in ambulatory than in nonambulatory patients, and some of these adverse reactions may be alleviated if the patient lies down.
Other adverse reactions include:
Central Nervous System: Drowsiness, mental clouding, lethargy, impairment of mental and physical performance, anxiety, fear, dysphoria, psychic dependence, mood changes.
Gastrointestinal System: Prolonged administration of NORCO (hydrocodone bitartrate and acetaminophen) ® may produce constipation.
Genitourinary System: Ureteral spasm, spasm of vesical sphincters and urinary retention have been reported with opiates.
Respiratory Depression: Hydrocodone bitartrate may produce dose-related respiratory depression by acting directly on the brain stem respiratory centers (see OVERDOSAGE).
Special Senses: Cases of hearing impairment or permanent loss have been reported predominantly in patients with chronic overdose.
Dermatological: Skin rash, pruritus.
The following adverse drug events may be borne in mind as potential effects of acetaminophen: allergic reactions, rash, thrombocytopenia, agranulocytosis. Potential effects of high dosage are listed in the OVERDOSAGE section.
DRUG ABUSE AND DEPENDENCE
Controlled Substance: NORCO (hydrocodone bitartrate and acetaminophen) ® is classified as a Schedule III controlled substance.
Abuse and Dependence: Psychic dependence, physical dependence, and tolerance may develop upon repeated administration of narcotics; therefore, this product should be prescribed and administered with caution. However, psychic dependence is unlikely to develop when NORCO (hydrocodone bitartrate and acetaminophen) ® is used for a short time for the treatment of pain.
Physical dependence, the condition in which continued administration of the drug is required to prevent the appearance of a withdrawal syndrome, assumes clinically significant proportions only after several weeks of continued narcotic use, although some mild degree of physical dependence may develop after a few days of narcotic therapy. Tolerance, in which increasingly large doses are required in order to produce the same degree of analgesia, is manifested initially by a shortened duration of analgesic effect, and subsequently by decreases in the intensity of analgesia. The rate of development of tolerance varies among patients.
Read the entire FDA prescribing information for Norco (Hydrocodone Bitartrate and Acetaminophen) »
Additional Norco Information
Norco 5/325 - User Reviews
Norco 5/325 User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Chronic Pain/Back Pain
Find tips and advances in treatment.