April 28, 2017
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Norflex Patient Information Including Side Effects

Brand Names: Norflex

Generic Name: orphenadrine (Pronunciation: or FEN a drin)

What is orphenadrine (Norflex)?

Orphenadrine is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain.

Orphenadrine is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury.

Orphenadrine may also be used for other purposes not listed in this medication guide.

Norflex 100 mg

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Orphenadrine 100 mg-EON

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Orphenadrine 100 mg-GLO

round, white, imprinted with 2011, G

What are the possible side effects of orphenadrine (Norflex)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using orphenadrine and call your doctor at once if you have any of these serious side effects:

  • fast, pounding, or uneven heartbeats;
  • confusion, anxiety, agitation, tremors, hallucinations;
  • seizure (convulsions); or
  • urinating less than usual or not at all.

Less serious side effects may include:

  • dry mouth or throat;
  • blurred vision, dilated pupils;
  • headache;
  • drowsiness, dizziness;
  • nausea, vomiting, constipation; or
  • weakness.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Read the Norflex (orphenadrine injection) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about orphenadrine (Norflex)?

Do not take this medication if you are allergic to orphenadrine, or if you have problems with urination, an enlarged prostate, glaucoma, a blockage in your stomach or intestines, trouble swallowing, or myasthenia gravis.

Do not crush, chew, or break the extended-release tablet. Swallow the pill whole. Breaking or crushing the pill may cause too much of the drug to be released at one time.

Orphenadrine may be habit-forming and should be used only by the person it was prescribed for. Orphenadrine should never be given to another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

Orphenadrine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol, which can increase some of the side effects of orphenadrine.

Side Effects Centers

Norflex - User Reviews

Norflex User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Norflex sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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