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Norgesic

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Norgesic

Norgesic

WARNINGS

Reye's Syndrome may develop in individuals who have chicken pox, influenza, or flu symptoms. Some studies suggest a possible association between the development of Reye's Syndrome and the use of medicines containing salicylate or aspirin. Norgesic (orphenadrine citrate with aspirin and caffeine) and Norgesic (orphenadrine citrate with aspirin and caffeine) Forte contain aspirin and therefore are not recommended for use in patients with chicken pox, influenza, or flu symptoms. Norgesic (orphenadrine citrate with aspirin and caffeine) and Norgesic (orphenadrine citrate with aspirin and caffeine) Forte may impair the ability of the patient to engage in potentially hazardous activities such as operating machinery or driving a motor vehicle; ambulatory patients should therefore be cautioned accordingly.

Aspirin should be used with extreme caution in the presence of peptic ulcers and coagulation abnormalities.

Usage In Pregnancy

Since safety of the use of this preparation in pregnancy, during lactation, or in the childbearing age has not been established, use of the drug in such patients requires that the potential benefits of the drug be weighed against its possible hazard to the mother and child.

Pediatric Use

Safety and effectiveness in pediatric patients have not been established.

PRECAUTIONS

Confusion, anxiety and tremors have been reported in a few patients receiving propoxyphene and orphenadrine concomitantly. As these symptoms may be simply due to an additive effect, reduction of dosage and/or discontinuation of one or both agents is recommended in such cases.

Safety of continuous long term therapy with Norgesic (orphenadrine citrate with aspirin and caffeine) and Norgesic (orphenadrine citrate with aspirin and caffeine) Forte has not been established; therefore, if Norgesic (orphenadrine citrate with aspirin and caffeine) or Norgesic (orphenadrine citrate with aspirin and caffeine) Forte is prescribed for prolonged use, periodic monitoring of blood, urine and liver function values is recommended.

Last reviewed on RxList: 4/7/2009
This monograph has been modified to include the generic and brand name in many instances.

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