Norgesic (Orphenadrine Citrate with Aspirin and Caffeine) Drug Information: Warnings and Precautions

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May 27, 2012

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Lower Back Pain »

Low back pain facts

Functions of the low back, or lumbar area, include structural support, movement, and protection of certain body tissues.
Pain in the low back can relate to the bony lumbar spine, discs between the vertebrae, ligaments around the spine and discs, spinal cord and nerves, muscles of the low back, internal organs of the pelvis and abdomen, and the skin covering the lumbar area.
Treatment of low back pain is optimally directed toward a diagnosed or suspected specific cause. For acute lumbar strain, use of a home remedy initially can be beneficial.

What is the anatomy of the low back?

The first step to understanding low back pain is appreciating the normal design (anatomy) of the tissues of this area of the body. Important structures of the low back that can be related to symptoms in this region include the bony lumbar spine (vertebrae, singular = vert...

Read the Lower Back Pain article »

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WARNINGS

Reye's Syndrome may develop in individuals who have chicken pox, influenza, or flu symptoms. Some studies suggest a possible association between the development of Reye's Syndrome and the use of medicines containing salicylate or aspirin. Norgesic (orphenadrine citrate with aspirin and caffeine) and Norgesic (orphenadrine citrate with aspirin and caffeine) Forte contain aspirin and therefore are not recommended for use in patients with chicken pox, influenza, or flu symptoms. Norgesic (orphenadrine citrate with aspirin and caffeine) and Norgesic (orphenadrine citrate with aspirin and caffeine) Forte may impair the ability of the patient to engage in potentially hazardous activities such as operating machinery or driving a motor vehicle; ambulatory patients should therefore be cautioned accordingly.

Aspirin should be used with extreme caution in the presence of peptic ulcers and coagulation abnormalities.

Usage In Pregnancy

Since safety of the use of this preparation in pregnancy, during lactation, or in the childbearing age has not been established, use of the drug in such patients requires that the potential benefits of the drug be weighed against its possible hazard to the mother and child.

Pediatric Use

Safety and effectiveness in pediatric patients have not been established.

PRECAUTIONS

Confusion, anxiety and tremors have been reported in a few patients receiving propoxyphene and orphenadrine concomitantly. As these symptoms may be simply due to an additive effect, reduction of dosage and/or discontinuation of one or both agents is recommended in such cases.

Safety of continuous long term therapy with Norgesic (orphenadrine citrate with aspirin and caffeine) and Norgesic (orphenadrine citrate with aspirin and caffeine) Forte has not been established; therefore, if Norgesic (orphenadrine citrate with aspirin and caffeine) or Norgesic (orphenadrine citrate with aspirin and caffeine) Forte is prescribed for prolonged use, periodic monitoring of blood, urine and liver function values is recommended.

Last reviewed on RxList: 4/7/2009
This monograph has been modified to include the generic and brand name in many instances.