"What are antidepressants and how do they work?
Antidepressants are a class of drugs that reduce symptoms of depressive disorders by correcting chemical imbalances of neurotransmitters in the brain. Chemical imbalances may be respo"...
Norpramin Patient Information including How Should I Take
In this Article
- What is desipramine (Norpramin)?
- What are the possible side effects of desipramine (Norpramin)?
- What is the most important information I should know about desipramine (Norpramin)?
- What should I discuss with my healthcare provider before taking desipramine (Norpramin)?
- How should I take desipramine (Norpramin)?
- What happens if I miss a dose (Norpramin)?
- What happens if I overdose (Norpramin)?
- What should I avoid while taking desipramine (Norpramin)?
- What other drugs will affect desipramine (Norpramin)?
- Where can I get more information?
What should I discuss with my healthcare provider before taking desipramine (Norpramin)?
Do not use this medication if you are allergic to desipramine, or if you have recently had a heart attack.
Do not use desipramine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take desipramine before the MAO inhibitor has cleared from your body.
If you have any of these other conditions, you may need a dose adjustment or special tests to safely take desipramine:
- heart disease, or a history of heart attack, stroke, or seizures;
- a family history of sudden death related to a heart rhythm disorder;
- bipolar disorder (manic-depression);
- schizophrenia or other mental illness;
- liver disease;
- overactive thyroid;
- diabetes (desipramine may raise or lower blood sugar);
- glaucoma; or
- problems with urination.
You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Tell your doctor if you have worsening symptoms of depression or suicidal thoughts during the first several weeks of treatment, or whenever your dose is changed.
Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.
Desipramine may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether desipramine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Older adults may be more likely to have side effects from this medication.
Do not give desipramine to anyone under 18 years old without the advice of a doctor.
How should I take desipramine (Norpramin)?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Your doctor may occasionally change your dose to make sure you get the best results from this medication. Follow the directions on your prescription label.
If you need to have any type of surgery, tell the surgeon ahead of time that you are taking desipramine. You may need to stop using the medicine for a short time.
Do not stop using desipramine without first talking to your doctor. You may need to use less and less before you stop the medication completely. Stopping this medication suddenly could cause you to have unpleasant side effects.
It may take a few weeks of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve during treatment.
Store desipramine at room temperature away from moisture and heat.
Additional Norpramin Information
- Norpramin Drug Interactions Center: desipramine oral
- Norpramin Side Effects Center
- Norpramin Overview including Precautions
- Norpramin FDA Approved Prescribing Information including Dosage
Norpramin - User Reviews
Norpramin User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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