Novolin N Innolet
"By Lisa Naingggolan
Medscape Medical News
The European Union has given the nod to a new formulation of insulin glargine (Toujeo, Sanofi), which is a higher-strength insulin (300 units/mL) than the existing insulin glargine"...
Novolin N Innolet
Insulin Use In Diabetes
Your physician has explained that you have diabetes and that your treatment involves injections of insulin or insulin therapy combined with an oral antidiabetic medicine. Insulin is normally produced by the pancreas, a gland that lies behind the stomach. Without insulin, glucose (a simple sugar made from digested food) is trapped in the bloodstream and cannot enter the cells of the body. Some patients who don't make enough of their own insulin, or who cannot use the insulin they do make properly, must take insulin by injection in order to control their blood glucose levels. Each case of diabetes is different and requires direct and continued medical supervision.
Your physician has told you the type, strength and amount of insulin you should use and the time(s) at which you should inject it, and has also discussed with you a diet and exercise schedule. You should contact your physician if you experience any difficulties or if you have questions.
Types of Insulins
Standard and purified animal insulins as well as human insulins are available. Standard and purified insulins differ in their degree of purification and content of noninsulin material. Standard and purified insulins also vary in species source; they may be of beef, pork, or mixed beef and pork origin. Human insulin is identical in structure to the insulin produced by the human pancreas, and thus differs from animal insulins. Insulins vary in time of action; see Product description for additional information.
Your physician has prescribed the insulin that is right for you; be sure you have purchased the correct insulin and check it carefully before you use it.
DOSAGE AND ADMINISTRATION
This package contains Novolin® N in an InnoLet® disposable prefilled insulin syringe. Novolin N is commonly known as NPH, Human Insulin Isophane Suspension (recombinant DNA origin). The concentration of this product is 100 units of insulin per milliliter. It is a cloudy or milky suspension of human insulin with protamine and zinc. The insulin substance (the cloudy material) settles at the bottom of the insulin reservoir, therefore, the Novolin N InnoLet (nph, human insulin isophane suspension 3 ml disposable prefilled syringe) must be rotated up and down so that the contents are uniformly mixed before a dose is given. Novolin N has an intermediate duration of action. The effect of Novolin N begins approximately 1½ hours after injection. The effect is maximal between 4 and 12 hours. The full duration of action may last up to 24 hours after injection.
Novolin N InnoLet (nph, human insulin isophane suspension 3 ml disposable prefilled syringe) should be stored in a cold (36° - 46°F [2° - 8°C]) place, preferably in a refrigerator, but not in the freezing compartment. Do not let it freeze. Keep Novolin N InnoLet (nph, human insulin isophane suspension 3 ml disposable prefilled syringe) in the carton so that it will stay clean and protected from light. The Novolin N InnoLet (nph, human insulin isophane suspension 3 ml disposable prefilled syringe) that you are currently using should not be refrigerated but should be kept as cool as possible (below 86°F [30° C]) and away from direct heat and light. Unrefrigerated Novolin N InnoLet (nph, human insulin isophane suspension 3 ml disposable prefilled syringe) must be discarded after 14 days, even if it still contains Novolin N.
Never use Novolin N InnoLet (nph, human insulin isophane suspension 3 ml disposable prefilled syringe) after the expiration date printed on the label and carton.
Never use any Novolin N InnoLet (nph, human insulin isophane suspension 3 ml disposable prefilled syringe) if the precipitate (the white deposit) has become lumpy or granular in appearance or has formed a deposit of solid particles on the wall of the insulin reservoir. This insulin should not be used if the liquid in the insulin reservoir remains clear after it has been mixed.
Helpful information for people with diabetes is published by American Diabetes Association, 1660 Duke Street, Alexandria, VA 22314
Date of issue: April 2004. Call 800-727-6500 for additional information. Novo Nordisk Pharmaceuticals, Inc. Princeton, NJ 08540. www.novonordisk-us.com. Manufactured by: Novo Nordisk A/S. DK-2880 Bagsvaerd, Denmark.
Novo Nordisk®, Novolin®, Lente®, NovoFine® and InnoLet® are trademarks owned by Novo Nordisk A/SThis monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 3/27/2009
Additional Novolin N Innolet Information
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