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Diabetes Prescription Insulin Medications »
Insulin is a hormone that is produced by certain cells in the pancreas called beta cells. Insulin helps the body use blood glucose (a type of sugar) for energy. When we eat and absorb food, glucose levels rise and insulin is released.
Some people can't make insulin; those people are said to have type 1 diabetes. A person with type 2 diabetes can make insulin, but the body doesn't respond well to insulin; they are said to have “insulin resistance.”
Insulin is always necessary for type 1 diabetes because the body has no internal source of insulin. People with type 2 diabetes may also need insulin, particularly those who have difficulty controlling their diabetes with oral medications.
Insulins differ based on three ...
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Novolin® R (recombinant dna origin)
Regular, Human Insulin Injection
(recombinant DNA origin) USP
Novolin® R (recombinant dna origin) Regular, Human Insulin Injection (rDNA origin) USP is a polypeptide hormone structurally identical to natural human insulin and is produced by rDNA technology utilizing Saccharomyces cerevisiae (bakers' yeast) as the production organism. Human insulin has the empirical formula C257H383N65O77S6 and a molecular weight of 5808 Da.
Figure 1. Structural formula of human insulin
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Novolin R (recombinant dna origin) is a sterile, clear, aqueous, and colorless solution, that contains human insulin (rDNA origin) 100 units/mL, glycerin 16 mg/ml, metacresol 3 mg/mL and zinc chloride approximately 7 µg/mL. The pH is adjusted to 7.4. Hydrochloric acid 2N and/or sodium hydroxide 2N may be added to adjust pH
Last reviewed on RxList: 4/17/2009
This monograph has been modified to include the generic and brand name in many instances.
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