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Novolin R

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Novolin R

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Novolin® R
(Regular, Human Insulin [rDNA origin] USP) Solution for Subcutaneous or Intravenous Use

DRUG DESCRIPTION

Novolin R (Regular Human Insulin Injection [Recombinant DNA origin] United States Pharmacopeia) is a polypeptide hormone structurally identical to native human insulin and is produced by recombinant DNA technology, utilizing Saccharomyces cerevisiae (baker's yeast) as the production organism. Novolin R has the empirical formula C257H383N65O77S6 and a molecular weight of 5808.

Figure 1: Structural formula of Novolin R

Novolin®
  R (Regular, Human Insulin [rDNA origin]) Structural formula of Novolin R Illustration

Novolin R is a sterile, clear, aqueous, and colorless solution that contains human insulin (rDNA origin) 100 units/mL, glycerol 16 mg/mL, metacresol 3 mg/mL, zinc chloride approximately 7 mcg/mL and water for injection. The pH is adjusted to 7.4. Hydrochloric acid 2N or sodium hydroxide 2N may be added to adjust pH. Novolin R vials are latex-free.

Last reviewed on RxList: 4/5/2012
This monograph has been modified to include the generic and brand name in many instances.

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