Novolin R (Recombinant DNA Origin) Patient Information: Side Effects and Drug Images at RxList

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May 27, 2012

Novolin R

Diabetes Prevention »

Introduction to diabetes prevention

I'm pretty lucky in my office practice. I have friendly patients who are usually already fairly well informed about their disease. They are also generally willing to have discussions about therapies and options.

What I have noticed (much to my delight) is that there are a growing number of patients coming to me for evaluation BEFORE they actually have developed diabetes, wanting to know how to prevent it. Most of them have seen family members with diabetes go through the process of diagnosis and management. As our attitude towards disease changes, and we learn to focus on prevention, I have more and more to discuss with these patients. Ultimately, I hope to see a paradigm shift where our focus is primarily on prevention of chronic diseases such as diabetes. For now, I hope this review provides some information to those of you wanting to make healthy lifestyle changes, and that it encourages you to open up a...

Read the Diabetes Prevention article »

Novolin R

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Novolin® R
(Regular, Human Insulin [rDNA origin] USP) Solution for Subcutaneous or Intravenous Use

DRUG DESCRIPTION

Novolin R (Regular Human Insulin Injection [Recombinant DNA origin] United States Pharmacopeia) is a polypeptide hormone structurally identical to native human insulin and is produced by recombinant DNA technology, utilizing Saccharomyces cerevisiae (baker's yeast) as the production organism. Novolin R has the empirical formula C₂₅₇H₃₈₃N₆₅O₇₇S₆ and a molecular weight of 5808.

Figure 1: Structural formula of Novolin R

Novolin®
R (Regular, Human Insulin [rDNA origin]) Structural formula of Novolin R Illustration

Novolin R is a sterile, clear, aqueous, and colorless solution that contains human insulin (rDNA origin) 100 units/mL, glycerol 16 mg/mL, metacresol 3 mg/mL, zinc chloride approximately 7 mcg/mL and water for injection. The pH is adjusted to 7.4. Hydrochloric acid 2N or sodium hydroxide 2N may be added to adjust pH. Novolin R vials are latex-free.

Last reviewed on RxList: 4/5/2012
This monograph has been modified to include the generic and brand name in many instances.