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Noxafil

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Noxafil

Noxafil Patient Information including How Should I Take

What should I discuss with my healthcare provider before using posaconazole (Noxafil)?

You should not use this medication if you are allergic to posaconazole or similar antifungals such as clotrimazole (Mycelex Troche), fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), miconazole (Oravig, Monistat), voriconazole (Vfend), and others.

Many drugs can interact with posaconazole and some should not be used at the same time. Tell your doctor about all other medications you use, especially:

  • cimetidine (Tagamet);
  • phenytoin (Dilantin);
  • pimozide (Orap);
  • quinidine (Quin-G);
  • rifabutin (Mycobutin);
  • sirolimus (Rapamune);
  • cholesterol lowering medicines such as atorvastatin (Lipitor, Caduet), lovastatin (Mevacor, Altoprev, Advicor), or simvastatin (Zocor, Simcor, Vytorin, Juvisync); or
  • ergot medicine such as ergotamine (Ergomar), dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), ergonovine (Ergotrate), or methylergonovine (Methergine).

To make sure you can safely take posaconazole, tell your doctor if you have any of these other conditions:

  • a personal or family history of Long QT syndrome;
  • liver disease; or
  • a heart rhythm disorder.

FDA pregnancy category C. It is not known whether posaconazole will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether posaconazole passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using posaconazole.

Do not give this medication to a child younger than 13 years old.

How should I take posaconazole (Noxafil)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Posaconazole works best if you take it within 20 minutes after a full meal or a nutritional supplement (such as Ensure).

Shake the oral suspension (liquid) well just before you measure a dose. Measure the liquid with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Call your doctor if you have ongoing vomiting or diarrhea. Posaconazole may not work as well while during this time.

To be sure this medication is not causing harmful effects, your blood may need to be tested often. Your liver function may also need to be tested. Visit your doctor regularly.

Take this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Posaconazole will not treat a viral infection such as the common cold or flu.

Store at room temperature away from moisture and heat. Do not freeze. Keep the bottle tightly closed when not in use.

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