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Noxafil

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Noxafil

Noxafil Patient Information Including Side Effects

Brand Names: Noxafil

Generic Name: posaconazole (Pronunciation: poe sa KONE a zole)

What is posaconazole (Noxafil)?

Posaconazole is an antifungal medication that fights certain infections caused by fungus.

Posaconazole is used to prevent fungal infections in people with weak immune systems resulting from certain treatments or conditions (such as chemotherapy, stem cell transplantation, HIV infection, and others).

Posaconazole is also used to treat oral thrush (yeast infection of the mouth).

Posaconazole may also be used for purposes not listed in this medication guide.

What are the possible side effects of posaconazole (Noxafil)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats;
  • slow heartbeats;
  • signs of an infection such as fever, chills, sore throat, flu symptoms, vomiting, mouth sores;
  • pale skin, easy bruising or bleeding, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling);
  • feeling like you might pass out;
  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain, shortness of breath, seizure).

Less serious side effects may include:

  • mild headache, dizziness;
  • tired feeling
  • swelling of your ankles or feet;
  • diarrhea, constipation, stomach pain;
  • joint or muscle pain; or
  • sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the Noxafil (posaconazole oral suspension) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about posaconazole (Noxafil)?

You should not use this medication if you are allergic to posaconazole or similar antifungals such as clotrimazole (Mycelex Troche), fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), miconazole (Oravig, Monistat), voriconazole (Vfend), and others.

You should not take posaconazole together with cimetidine (Tagamet), phenytoin (Dilantin), pimozide (Orap), quinidine (Quin-G), rifabutin (Mycobutin), sirolimus (Rapamune), atorvastatin (Lipitor, Caduet), lovastatin (Mevacor, Altoprev, Advicor), simvastatin (Zocor, Simcor, Vytorin, Juvisync), or an ergot medicine such as ergotamine (Ergomar), dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), ergonovine (Ergotrate), or methylergonovine (Methergine).

Take this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Posaconazole will not treat a viral infection such as the common cold or flu.

Call your doctor if you have ongoing vomiting or diarrhea. Posaconazole may not work as well while during this time.

Side Effects Centers
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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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