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Patients should be advised of the following information:

- NUBAIN (nalbuphine hydrochloride) is associated with sedation and may impair mental and physical abilities required for the performance of potentially dangerous tasks such as driving a car or operating machinery.

- NUBAIN (nalbuphine hydrochloride) is to be used as prescribed by a physician. Dose or frequency should not be increased without first consulting with a physician since NUBAIN (nalbuphine hydrochloride) may cause psychological or physical dependence.

- The use of NUBAIN (nalbuphine hydrochloride) with other opioids can cause signs and symptoms of withdrawal.

- Abrupt discontinuation of NUBAIN (nalbuphine hydrochloride) after prolonged usage may cause signs and symptoms of withdrawal.

Last reviewed on RxList: 1/4/2008
This monograph has been modified to include the generic and brand name in many instances.

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