May 26, 2017
Recommended Topic Related To:


"Patients with moderate-to-severe asthma and sputum eosinophilia benefited from fevipiprant in a single-center, randomized trial published online August 5 in Lancet Respiratory Medicine.

The results are the latest to suggest tar"...



(mepolizumab) for Subcutaneous Injection


Mepolizumab is a humanized IL-5 antagonist monoclonal antibody. Mepolizumab is produced by recombinant DNA technology in Chinese hamster ovary cells. Mepolizumab has a molecular weight of approximately 149 kDa.

NUCALA is supplied as a sterile, white to off-white, preservative-free, lyophilized powder for subcutaneous injection after reconstitution. Upon reconstitution with 1.2 mL of Sterile Water for Injection, USP [see DOSAGE AND ADMINISTRATION], the resulting concentration is 100 mg/mL and delivers 1 mL. Each single-dose vial delivers mepolizumab 100 mg, polysorbate 80 (0.67 mg), sodium phosphate dibasic heptahydrate (7.14 mg), and sucrose (160 mg), with a pH of 7.0.

Last reviewed on RxList: 3/2/2017
This monograph has been modified to include the generic and brand name in many instances.

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Allergies & Asthma

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