May 26, 2017
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Nulojix Patient Information Including Side Effects

Brand Names: Nulojix

Generic Name: belatacept (Pronunciation: bel AT a sept)

What is belatacept (Nulojix)?

Belacept lowers your body's immune system. The immune system helps your body fight infections. The immune system can also fight or "reject" a transplanted organ such as a kidney. This is because the immune system treats the new organ as an invader.

Belatacept is used in combination with other medications to prevent organ rejection after a kidney transplant.

Belatacept may also be used for purposes not listed in this medication guide.

What are the possible side effects of belatacept (Nulojix)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Serious and sometimes fatal infections may occur during treatment with belatacept. Call your doctor right away if you have signs of infection such as:

  • fever, night sweats, tired feeling;
  • cough, sore throat, swollen glands;
  • flu symptoms, weight loss;
  • confusion, change in your mental state;
  • problems with thinking or memory;
  • problems with speech or walking,
  • decreased vision;
  • stomach pain, vomiting, diarrhea;
  • tenderness on the side where you received the transplanted kidney;
  • a new bump or lesion on your skin, or a mole that has changed in size or color; or
  • blood in your urine, pain or burning when you urinate, urinating less than usual or not at all.

Call your doctor at once if you have a serious side effect such as:

  • pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;
  • wheezing, chest tightness, trouble breathing;
  • high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling);
  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling);
  • high blood sugar (increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss); or
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious side effects may include:

  • nausea, constipation;
  • headache, back pain, joint pain;
  • cold symptoms such as runny or stuffy nose, sneezing
  • sleep problems (insomnia); or
  • swelling in your hands or feet.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the Nulojix (belatacept) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about belatacept (Nulojix)?

You should not use belatacept if you have received a liver transplant. Before you start treatment with belatacept, your doctor will perform tests to make sure you are immune to Epstein-Barr virus (EBV-positive). Your risk of serious infection is higher if you have never been exposed to EBV.

Treatment with belatacept may increase your risk of developing certain life-threatening conditions, including serious infections, cancer, or transplant failure. Talk with your doctor about the risks and benefits of using this medication.

Serious infections that have occurred in people using belatacept include tuberculosis, a severe brain infection, or a virus that can cause failure of a transplanted kidney.

Call your doctor right away if you have signs of infection such as: fever, night sweats, swollen glands, flu symptoms, change in your mental state, problems with speech or walking, decreased vision, tenderness of your transplanted kidney, a new skin lesion, a mole that has changed in size or color, pain or burning when you urinate, blood in your urine, or urinating less than usual or not at all.

You will need regular medical tests to be sure this medication is not causing harmful effects. Visit your doctor regularly.

Side Effects Centers

Additional Nulojix Information

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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