"The U.S. Food and Drug Administration today approved Dotarem (gadoterate meglumine) for use in magnetic resonance imaging (MRI) of the brain, spine and associated tissues of patients ages 2 years and older.
Dotarem is a gadolinium-based"...
OCUCOAT (hydroxypropylmethylcellulose) is a sterile, isotonic, nonpyrogenic viscoelastic solution of highly purified, noninflammatory, 2% hydroxypropylmethylcellulose with a high molecular weight greater than 80,000 daltons. OCUCOAT (hydroxypropylmethylcellulose) is supplied in 1 mL syringes. Each mL provides 20 mg/mL of hydroxypropylmethylcellulose dissolved in a physiological balanced salt solution containing 0.49% sodium chloride, 0.075% potassium chloride, 0.048% calcium chloride, 0.03% magnesium chloride, 0.39% sodium acetate, 0.17% sodium citrate and water for injection. The osmolarity of OCUCOAT (hydroxypropylmethylcellulose) is 285 ± 32 mOsM, the viscosity is 4000 ± 1500 cst, and the pH is 7.2±0.4.
OCUCOAT (hydroxypropylmethylcellulose) :
- Is a space occupying, tissue protective substance
- Exhibits excellent flow properties
- Is completely transparent
- Is nonantigenic
- Is easily removed from the anterior chamber
- Contains no proteins which may cause inflammation or foreign body reactions
- Requires no refrigeration or restrictive storage conditions
- Does not interfere with normal wound healing process
- Clears the trabecular meshwork in 24 hours (98% clearance rate)
Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.
Additional Ocucoat Information
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