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The eyes are complex sensory organs. About 85% of the total sensory input to our brains originates from our sense of sight, while the other 15% comes from the other four senses of hearing, smell, touch, and taste. The eyes are designed to optimize vision under conditions of varying light. Their location, on the outside of the face, makes them susceptible to trauma, environmental chemicals and particles, and infectious agents. The eyelids and the position of the eye within the bony orbital cavity are the major protective mechanism for the eye.
The eye itself has the shape of a sphere measuring about 1 inch in diameter. It consists of a clear, transparent dome at the front (the cornea) that is surrounded by the white of the eyeball (the sclera). The iris of the eye is the circular, colored portion within the eye, and behind the cornea, and the pupil is the central opening within the iris. Behind the iris and pupil is the e...
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Transient burning and stinging upon instillation and other minor symptoms of ocular irritation have been reported with the use of OCUFEN® (flurbiprofen sodium ophthalmic solution) ophthalmic solution. Other adverse reactions reported with the use of OCUFEN® (flurbiprofen sodium ophthalmic solution) ophthalmic solution include: fibrosis, miosis, and mydriasis.
Increased bleeding tendency of ocular tissues in conjunction with ocular surgery has also been reported.
Interaction of OCUFEN® (flurbiprofen sodium ophthalmic solution) ophthalmic solution with other topical ophthalmic medications has not been fully investigated.
Although clinical studies with acetylcholine chloride and animal studies with acetylcholine chloride or carbachol revealed no interference, and there is no known pharmacological basis for an interaction, there have been reports that acetylcholine chloride and carbachol have been ineffective when used in patients treated with OCUFEN® (flurbiprofen sodium ophthalmic solution) ophthalmic solution.
Last reviewed on RxList: 12/30/2008
This monograph has been modified to include the generic and brand name in many instances.
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