July 25, 2016
Recommended Topic Related To:


"The US Food and Drug Administration (FDA) has approved a riboflavin ophthalmic solution (Photrexa, Avedro) that treats a corneal disease called progressive keratoconus with corneal collagen crosslinking, the manufacturer announced today."...



How Supplied


OCUFLOX (ofloxacin ophthalmic) ® ophthalmic solution is indicated for the treatment of infections caused by susceptible strains of the following bacteria in the conditions listed below:

Gram-positive bacteria: Gram-negative bacteria:
Staphylococcus aureus Enterobacter cloacae
Staphylococcus epidermidis Haemophilus influenzae
Streptococcus pneumoniae Proteus mirabilis
  Pseudomonas aeruginosa
Gram-positive bacteria: Gram-negative bacteria:
Staphylococcus aureus Pseudomonas aeruginosa
Staphylococcus epidermidis Serratia marcescens*
Streptococcus pneumoniae Anaerobic species:
  Propionibacterium acnes
*Efficacy for this organism was studied in fewer than 10 infections


The recommended dosage regimen for the treatment of bacterial conjunctivitis is:

Days 1 and 2 Instill one to two drops every two to four hours in the affected eye(s).
Days 3 through 7 Instill one to two drops four times daily.
The recommended dosage regimen for the treatment of bacterial corneal ulcer is:
Days 1 and 2 Instill one to two drops into the affected eye every 30 minutes, while awake. Awaken at approximately four and six hours after retiring and instill one to two drops.
Days 3 through 7 to 9 Instill one to two drops hourly, while awake.
Days 7 to 9 through treatment completion Instill one to two drops, four times daily.


OCUFLOX® (ofloxacin ophthalmic solution) 0.3% is supplied sterile in opaque white LDPE plastic bottles and white dropper tips with beige high impact polystyrene (HIPS) caps as follows:

5mL in 10mL bottle - NDC 11980-779-05

Note: Store at 15-25°C (59-77°F)

Rev May 2005. Allergan, Inc. Irvine, CA 92612, U.S.A. Licensed from: Daiichi Pharmaceutical Co., Ltd., Tokyo, Japan and Santen Pharmaceutical Co., Ltd., Osaka, Japan

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 5/6/2009

How Supplied

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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