July 26, 2016
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Ofloxacin Ophthalmic Solution

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Ofloxacin Ophthalmic Solution

How Supplied


Ofloxacin ophthalmic solution is indicated for the treatment of infections caused by susceptible strains of the following bacteria in the conditions listed below:

Gram-positive bacteria: Gram-negative bacteria:  
Staphylococcus aureus Enterobacter cloacae
Staphylococcus epidermidis Haemophilus influenzae
Streptococcus pneumoniae Proteus mirabilis Pseudomonas aeruginosa
Gram-positive bacteria: Gram-negative bacteria: Anaerobic species:
Staphylococcus aureus Pseudomonas aeruginosa Propionibacterium acnes
Staphylococcus epidermidis Serratia marcescens*  
Streptococcus pneumoniae  
*Efficacy for this organism was studied in fewer than 10 infections


The recommended dosage regimen for the treatment of bacterial conjunctivitis is:

Days 1 and 2 ..... Instill one to two drops every two to four hours in the affected eye(s).

Days 3 through 7 ..... Instill one to two drops four times daily.

The recommended dosage regimen for the treatment of bacterial corneal ulcer is:

Days 1 and 2 .... Instill one to two drops into the affected eye every 30 minutes, while awake. Awaken at approximately four and six hours after retiring and instill one to two drops.

Days 3 through 7 to 9 .... Instill one to two drops hourly, while awake.

Days 7 to 9 through treatment completion .... Instill one to two drops, four times daily.


Ofloxacin Ophthalmic Solution is supplied sterile in plastic dropper bottles of the following sizes:

5mL-NDC 17478-713-10
10mL-NDC 17478-713-11


Store at 20° to 25°C (68° to 77T). [See USP Controlled Room Temperature].

Akorn Inc. Buffalo Grove, IL 60089. FDA Rev date: 5/14/2004

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 1/21/2009

How Supplied

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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