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Oforta Patient Information including How Should I Take

What should I discuss with my healthcare provider before I take fludarabine (Oforta)?

You should not use this medication if you are allergic to fludarabine, or if you are also being treated with a cancer medicine called pentostatin (Nipent).

If you have any of these other conditions, you may need a fludarabine dose adjustment or special tests:

  • kidney disease;
  • bone marrow problems; or
  • a weak immune system.

FDA pregnancy category D. Do not use fludarabine if you are pregnant. It could harm the unborn baby.

Use birth control to prevent pregnancy while you are taking fludarabine, whether you are a man or a woman. Keep using birth control for at least 6 months after your treatment ends. Fludarabine use by either parent may cause birth defects.

It is not known whether fludarabine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are taking fludarabine.

How should I take fludarabine (Oforta)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Fludarabine is usually taken daily for 5 days in a row every 28 days. Once your body has responded well to the medication, your doctor may recommend additional treatment cycles.

Fludarabine may be taken with or without food.

Do not crush, chew, or break a fludarabine tablet.

Swallow the tablet whole with water.

Do not use a tablet that has been accidentally broken. The powder from a crushed or broken pill can be dangerous if you breathe it in, or if it gets in your eyes, mouth, or nose, or on your skin. Ask your doctor or pharmacist how to safely handle and dispose of a broken tablet.

If you accidentally touch a broken tablet, wash your skin with soap and water. Call your doctor if you develop a skin rash or severe irritation.

If the powder from a broken tablet gets in your eyes, rinse them with water for at least 15 minutes.

Fludarabine can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill.

Contact your doctor at once if you develop signs of infection such as fever, cough, sore throat, flu symptoms, easy bruising or bleeding (nosebleeds, bleeding gums), loss of appetite, nausea and vomiting, mouth sores, or unusual weakness.

Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests. Visit your doctor regularly.

If you need to have a blood transfusion, tell your caregivers ahead of time that you are taking fludarabine.

Keep each tablet in its blister pack until you are ready to take it. Push a tablet through the foil when you are ready to take the medicine.

Do not allow other people to handle a fludarabine tablet. Keep the medicine in a place where children and pets cannot get to it.

Store at room temperature away from moisture and heat.

Do not throw away unused or expired fludarabine tablets in your household trash. Ask your pharmacist where to locate a community pharmaceutical take back disposal program.

Side Effects Centers

Oforta - User Reviews

Oforta User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Oforta sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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