"For adults and children who undergo cataract surgery, implantation of an artificial lens is the standard of care. But a clinical trial suggests that for most infants, surgery followed by the use of contact lenses for several years â€” and an eventu"...
(phenylephrine and ketorolac) Injection
Omidria is a sterile aqueous solution concentrate containing the α1-adrenergic receptor agonist phenylephrine HCl and the nonsteroidal anti-inflammatory ketorolac tromethamine.
The descriptions and structural formulae are:
Phenylephrine Hydrochloride Drug Substance:
Common Name: phenylephrine hydrochloride
Chemical Name: (-)-m-Hydroxy-α-[(methylamino)methyl]benzyl alcohol hydrochloride
Molecular Formula: C9H13NO2• HCl Molecular Weight: 203.67 g/mole
Figure 1: Chemical Structure for Phenylephrine HCl
Ketorolac Tromethamine Drug Substance:
Common Name: ketorolac tromethamine
Chemical Name: (±)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
Molecular Formula: C15H13NO3 • C4H11NO3
Molecular Weight: 376.40 g/mole
Figure 2: Chemical Structure
for Ketorolac Tromethamine
Each vial of Omidria contains
Actives: phenylephrine hydrochloride 12.4 mg/mL equivalent to 10.16 mg/mL of phenylephrine and ketorolac tromethamine 4.24 mg/mL equivalent to 2.88 mg/mL of ketorolac.
Inactives: citric acid monohydrate; sodium citrate dihydrate; water for injection; may include sodium hydroxide and/or hydrochloric acid for pH adjustment.
Last reviewed on RxList: 6/16/2014
This monograph has been modified to include the generic and brand name in many instances.
Additional Omidria Information
Report Problems to the Food and Drug Administration
Find out what women really need.