Omnaris (Ciclesonide Nasal Spray) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Omnaris

Nasal Allergy Medications »

Introduction

Although they are the cornerstone of allergy treatment, avoidance measures are not always enough to manage all of the symptoms. When the symptoms of nasal allergies are mild or intermittent, antihistamines with or without decongestants can help. Very often, some relief can be found in taking over-the-counter (OTC) drugs and this is usually the first step an allergy sufferer will take. Self-medication, though, is frequently inadequate since OTC drugs cannot adequately treat the inflammation that develops in the nose. At this stage, anti-inflammatory medications are required, usually in the form of intra- nasal steroid sprays (sprayed into the nose).

The combination of an antihistamine (with or without a decongestant) and a topical nasal steroid spray will usually afford good relief with minimal side effects. The addition of ipratropium bromide nasal spray (Atrovent - an anticholinergic medication) is also very effec...

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Omnaris

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OMNARIS®
(ciclesonide) Nasal Spray

For Nasal Inhalation Only

DRUG DESCRIPTION

The active component of OMNARIS Nasal Spray is ciclesonide, a non-halogenated glucocorticoid having the chemical name pregna -1,4-diene-3,20-dione, 16,17-[[R cyclohexylmethylene]bis(oxy)]-11-hydroxy-21-(2-methyl-1-oxopropoxy)-,(11β,16α)-. Ciclesonide is delivered as the R-epimer. The empirical formula is C₃₂H₄₄O₇ and its molecular weight is 540.7. Its structural formula is as follows:

OMNARIS® (ciclesonide) Structural Formula Illustration

Ciclesonide is a white to yellow-white powder, practically insoluble in water and freely soluble in ethanol and acetone. OMNARIS (ciclesonide nasal spray) Nasal Spray is a metered-dose, manual pump spray formulation containing a hypotonic aqueous suspension of ciclesonide. OMNARIS (ciclesonide nasal spray) Nasal Spray also contains microcrystalline cellulose, carboxymethylcellulose sodium, hypromellose, potassium sorbate and edetate sodium; and hydrochloric acid to adjust the pH to 4.5.

What are the possible side effects of ciclesonide nasal (Omnaris)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Although it is not likely that your body will absorb enough of this medication to cause serious side effects, tell your doctor if you have any of these steroid-related symptoms:

irregular menstrual periods;
acne or increased hair growth;
swelling, rapid weight gain, roundness of the face;
increased sweating; or

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What are the precautions when taking ciclesonide nasal spray (Omnaris)?

Before using ciclesonide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: recent nasal ulcers/trauma/surgery, tuberculosis (untreated or active infections), herpes infection of the eye, decreased adrenal gland function, a certain eye disease (glaucoma).

Avoid exposure to chickenpox or measles infection while using this medication. If you are exposed to these infections, seek immediate medical attention.

Rarely, using corticosteroid medications for a long time can make it more...

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Last reviewed on RxList: 6/7/2010
This monograph has been modified to include the generic and brand name in many instances.