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Oncaspar

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Oncaspar

OVERDOSE

Three patients received 10,000 International Units/m² of Oncaspar® as an intravenous infusion. One patient experienced a slight increase in liver enzymes. A second patient developed a rash 10 minutes after the start of the infusion, which was controlled with the administration of an antihistamine and by slowing down the infusion rate. A third patient did not experience any adverse reactions.

CONTRAINDICATIONS

  • History of serious allergic reactions to Oncaspar® .
  • History of serious thrombosis with prior L-asparaginase therapy.
  • History of pancreatitis with prior L-asparaginase therapy.
  • History of serious hemorrhagic events with prior L-asparaginase therapy.

Last reviewed on RxList: 5/2/2014
This monograph has been modified to include the generic and brand name in many instances.

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