home > drugs a-z list > onfi (clobazam) drug center > onfi (clobazam) drug

Recommended Topic Related To:

Onfi

Generalized seizures

There are six types of generalized seizures. The most common and dramatic, and therefore the most well known, is the generalized convulsion, also called the grand-mal seizure. In this type of seizure, the patient loses consciousness and usually collapses. The loss of consciousness is followed by generalized body stiffening (called the "tonic" phase of the seizure) for 30 to 60 seconds, then by violent jerking (the "clonic" phase) for 30 to 60 seconds, after which the patient goes into a deep sleep (the "postictal" or after-seizure phase). During grand-mal seizures, injuries and accidents may occur, such as tongue biting and urinary incontinence.

Absence seizures cause a short loss of consciousness (just a few seconds) with few or no symptoms. The patient, most often a child, typically interrupts an activity and stares blankly. These seizures begin and end abruptly and may occur several times a day. Patients are usu...

Onfi

font size

ONFI™
(clobazam) Tablets, for Oral Use

DRUG DESCRIPTION

Table 4. Description

Proprietary Name: ONFIIM
Established Name: Clobazam
Dosage Form: Tablet
Route of Administration: Oral
Pharmacologic Class of Drug: Antiepileptic drug of the benzodiazepine class
Chemical Name: 7-Chloro-1-methyl-5-phenyl-1 H-1 ,5 benzodiazepine-2,4(3H,5H)-dione

Structural Formula:

ONFI™
  (clobazam) Structural Formula Illustration

Each ONFI tablet contains 5 mg, 10 mg, or 20 mg of clobazam. Tablets also contain as inactive ingredients: corn starch, lactose monohydrate, magnesium stearate, silicon dioxide, and talc. The molecular formula is C16H13O2N2Cl and the molecular weight is 300.7.

Clobazam is a white or almost white, crystalline powder which is freely soluble in methylene chloride, slightly soluble in water, and sparingly soluble in ethanol. The melting range of clobazam is from 182-185°C.

Last reviewed on RxList: 10/31/2011
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Epilepsy

Find tips and treatments to control seizures.