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The major goal in treating diabetes is to minimize any elevation of blood sugar (glucose) without causing abnormally low levels of blood sugar. Type 1 diabetes is treated with insulin, exercise, and a diabetic diet. Type 2 diabetes is treated first with weight reduction, a diabetic diet, and exercise. When these measures fail to control the elevated blood sugars, oral medications are used. If oral medications are still insufficient, treatment with insulin is considered.
Adherence to a diabetic diet is an important aspect of controlling elevated blood sugar in patients with diabetes. The American Diabetes Association (ADA) has provided guidelines for a diabetic diet. The ADA diet is a balanced, nutritious diet that is low in fat, cholesterol, and simple sugars. The total daily calories are evenly divided into three meals. In the past two years, the ADA has lifted the absolute ban on simple sugars. Small amounts of si...
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Medical Editor: John P. Cunha, DO, FACOEP
Onglyza (saxagliptin) is used either alone or with other medications, and with a proper diet and exercise program, to control high blood sugar. It is used in people with type 2 (non-insulin-dependent) diabetes. Common side effects include runny or stuffy nose, sore throat, cough, headache, or stomach pain.
The recommended dose of Onglyza is 2.5 mg or 5 mg once daily taken regardless of meals. Onglyza may interact with tazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, ritonavir, saquinavir, and telithromycin. Low blood sugar may occur if this drug is prescribed with other anti-diabetes medications. During pregnancy, Onglyza should be used only when prescribed. Pregnancy may cause or worsen diabetes. Your doctor may change your diabetes treatment during your pregnancy. It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.
Our Onglyza (saxagliptin) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
ONGLYZA is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus in multiple clinical settings. [See Clinical Studies.]
ONGLYZA should not be used for the treatment of type 1 diabetes mellitus or diabetic ketoacidosis, as it would not be effective in these settings.
ONGLYZA has not been studied in patients with a history of pancreatitis. It is unknown whether patients with a history of pancreatitis are at an increased...
Read the complete drug monograph for Onglyza »
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
This drug works by increasing levels of natural substances called incretins. Incretins help to control blood sugar by increasing insulin release, especially after a meal. They also dec...
Read the complete consumer information for Onglyza »
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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