Brand Names: Opana, Opana ER

Generic Name: oxymorphone (Pronunciation: ox ee MOR fone)

• What is oxymorphone (Opana ER)?
• What are the possible side effects of oxymorphone (Opana ER)?
• What is the most important information I should know about oxymorphone (Opana ER)?
• What should I discuss with my healthcare provider before using oxymorphone (Opana ER)?
• How should I use oxymorphone (Opana ER)?
• What happens if I miss a dose (Opana ER)?
• What happens if I overdose (Opana ER)?
• What should I avoid while using oxymorphone (Opana ER)?
• What other drugs will affect oxymorphone (Opana ER)?
• Where can I get more information?

What is oxymorphone (Opana ER)?

Oxymorphone is in a group of drugs called narcotic pain relievers. It is similar to morphine.

Oxymorphone is used to treat moderate to severe pain. The extended-release form of this medication is for around-the-clock treatment of pain.

Oxymorphone is not for treating pain just after surgery unless you were already taking oxymorphone before the surgery.

Oxymorphone may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of oxymorphone (Opana ER)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• shallow breathing, slow heartbeat;
• seizure (convulsions);
• cold, clammy skin;
• confusion;
• severe weakness or dizziness; or
• feeling light-headed, fainting.

Less serious side effects are more likely to occur, such as:

• nausea, vomiting, constipation;
• dizziness, headache;
• dry mouth;
• sweating; or
• itching.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Read the Opana ER (oxymorphone hydrochloride extended release) Side Effects Center for a complete guide to possible side effects »

What is the most important information I should know about oxymorphone (Opana ER)?

Oxymorphone may be habit-forming and should be used only by the person it was prescribed for. Oxymorphone should never be given to another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

Do not drink alcohol while you are taking oxymorphone. Dangerous side effects or death can occur when alcohol is combined with a narcotic pain medicine. Check your food and medicine labels to be sure these products do not contain alcohol.

Never take more than your prescribed dose of oxymorphone. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Oxymorphone can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.